Tuesday, July 1, 2025

Lazard Welcomes Klaus H. Hessberger as Managing Director and Global Co-Head of Financial Sponsors Group

 LONDON - Tuesday, 01. July 2025 AETOSWire  



(BUSINESS WIRE)--Lazard, Inc. (NYSE: LAZ) today announced that Klaus H. Hessberger has been appointed to the firm as Managing Director, Global Co-Head, and Head of Europe for Lazard’s Financial Sponsors Group, based in London.


Adam Cady, previously Lazard’s Head of Large-Cap Financial Sponsor Coverage North America in New York, has also been named Global Co-Head of the Global Financial Sponsors Group, running the team together with Klaus.


These appointments reflect Lazard’s expanding connectivity and partnership with alternative asset managers, which continues to be a principal area of focus and a major source of future growth for the firm globally. Lazard’s recruiting efforts are also a key contributor to the firm’s long-term growth goals, with ongoing success in attracting top tier talent globally.


“Klaus is a recognised leader in the global financial sponsor community with an impressive track record of advising global alternative asset managers and leading teams of highly experienced industry professionals,” said Peter R. Orszag, CEO and Chairman. “Together with Adam, who has played a pivotal role in managing Lazard’s relationships with the world’s largest alternative asset managers, we are well-positioned to further advance our market-leading offering to financial sponsor clients in Europe and globally.”


“I’m thrilled to join Lazard, a firm with a rich history and an unparalleled reputation for excellence in advising financial sponsor and corporate clients around the world. Lazard’s leading global industry, sector and product platform and innovative approach ensure the firm’s clients succeed in an increasingly complex investment landscape. Working alongside Adam and the talented team, I’m excited to build on Lazard’s strong foundations and deliver meaningful results for our clients,” said Klaus H. Hessberger.


Before joining Lazard, Klaus held various prominent roles over 25 years with J.P. Morgan, helping to build and co-running their market-leading European and later Global Financial Sponsors franchise, initially as European and later Global Co-Head. Klaus has most recently served as Vice Chair of the Global Financial Sponsors and Strategic Investors Coverage Group at J.P. Morgan.


In these roles, Klaus covered top-tier global financial sponsor and strategic investor clients, including private equity and infrastructure funds, family offices, sovereign wealth and pension funds. In addition to his Financial Sponsor track record, Klaus brings a broad range of global industry sector and capital markets expertise, having previously co-run J.P. Morgan’s Equity Capital Markets origination business in EMEA for nine years.


Adam Cady has nearly three decades of experience in investment banking and capital markets. Prior to joining Lazard’s New York office in February 2024, Adam held various senior positions at Bank of America, departing as Managing Director and Head of Americas Financial Sponsors Group. He started his career as a leveraged finance professional at Merrill Lynch and NationsBank.


About Lazard


Founded in 1848, Lazard is the preeminent financial advisory and asset management firm, with operations in North and South America, Europe, the Middle East, Asia, and Australia. Lazard provides advice on mergers and acquisitions, capital markets and capital solutions, restructuring and liability management, geopolitics, and other strategic matters, as well as asset management and investment solutions to institutions, corporations, governments, partnerships, family offices, and high net worth individuals. For more information, please visit Lazard.com and follow Lazard on LinkedIn.


 


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Contacts

Media Contacts


Poppy Trowbridge

+44 020 7187 2065

Poppy.Trowbridge@lazard.com


Jessica Francisco

+1 212 632 6571

Jessica.Francisco@lazard.com


 

Galderma Announces Departure of Its Chief Financial Officer

 Ad hoc announcement pursuant to Art. 53 LR


(BUSINESS WIRE)--Galderma Group AG (SIX:GALD), the pure-play dermatology category leader, today announced that Thomas Dittrich, Chief Financial Officer, will be leaving the company to pursue another senior executive opportunity outside the organization.


“We thank Thomas for his financial leadership and many contributions during his time at Galderma. He played a key role in establishing the financial discipline, operational readiness, and strategic clarity that will continue to guide us forward. We wish him every success in his next role and remain focused on further accelerating Galderma’s strong growth – from category leadership to becoming a true powerhouse in dermatology.”


FLEMMING ØRNSKOV, M.D., MPH

CHIEF EXECUTIVE OFFICER

GALDERMA


Thomas Dittrich will remain with the company as Chief Financial Officer through Q2 2026 to ensure a seamless transition through the close of the 2025 fiscal year. A successor will be announced in due course.


“I want to thank Flemming, our Board of Directors, our investors, and all my colleagues at Galderma for their support throughout what has been the most impactful transformation and growth journey of my career. I leave holding Galderma in the highest regard, enormously proud of the strides we’ve made together, and equally excited about Galderma’s continued growth momentum and long-term success.”


THOMAS DITTRICH

CHIEF FINANCIAL OFFICER

GALDERMA


About Galderma

Galderma (SIX: GALD) is the pure-play dermatology category leader, present in approximately 90 countries. We deliver an innovative, science-based portfolio of premium flagship brands and services that span the full spectrum of the fast-growing dermatology market through Injectable Aesthetics, Dermatological Skincare and Therapeutic Dermatology. Since our foundation in 1981, we have dedicated our focus and passion to the human body’s largest organ – the skin – meeting individual consumer and patient needs with superior outcomes in partnership with healthcare professionals. Because we understand that the skin we are in shapes our lives, we are advancing dermatology for every skin story. For more information: www.galderma.com.


Forward-looking statements

Certain statements in this announcement are forward-looking statements. Forward-looking statements are statements that are not historical facts and may be identified by words such as "plans", "targets", "aims", " believes", "expects", "anticipates", "intends", "estimates", "will", "may", "continues", "should" and similar expressions. These forward-looking statements reflect, at the time, Galderma's beliefs, intentions and current targets/ aims concerning, among other things, Galderma's results of operations, financial condition, industry, liquidity, prospects, growth and strategies and are subject to change. The estimated financial information is based on management's current expectations and is subject to change. By their nature, forward-looking statements involve a number of risks, uncertainties and assumptions that could cause actual results or events to differ materially from those expressed or implied by the forward-looking statements. These risks, uncertainties and assumptions could adversely affect the outcome and financial consequences of the plans and events described herein. Actual results may differ from those set forth in the forward-looking statements as a result of various factors (including, but not limited to, future global economic conditions, changed market conditions, intense competition in the markets in which Galderma operates, costs of compliance with applicable laws, regulations and standards, diverse political, legal, economic and other conditions affecting Galderma’s markets, and other factors beyond the control of Galderma). Neither Galderma nor any of their respective shareholders (as applicable), directors, officers, employees, advisors, or any other person is under any obligation to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise. You should not place undue reliance on forward-looking statements, which speak of the date of this announcement. Statements contained in this announcement regarding past trends or events should not be taken as a representation that such trends or events will continue in the future. Some of the information presented herein is based on statements by third parties, and no representation or warranty, express or implied, is made as to, and no reliance should be placed on, the fairness, reasonableness, accuracy, completeness or correctness of this information or any other information or opinions contained herein, for any purpose whatsoever. Except as required by applicable law, Galderma has no intention or obligation to update, keep updated or revise this announcement or any parts thereof.


 

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Contacts

For further information:


Christian Marcoux, M.Sc.

Chief Communications Officer

christian.marcoux@galderma.com

+41 76 315 26 50


Richard Harbinson

Corporate Communications Director

richard.harbinson@galderma.com

+41 76 210 60 62


Emil Ivanov

Head of Strategy, Investor Relations, and ESG

emil.ivanov@galderma.com

+41 21 642 78 12


Jessica Cohen

Investor Relations and Strategy Director

jessica.cohen@galderma.com

+41 21 642 76 43

Monetate Acquires SiteSpect to Deliver AI-Native Personalization and Testing at Enterprise Scale

 


Monetate’s Real-Time Personalization Unites with SiteSpect’s Zero-Flicker Testing to Optimize Digital Experiences with Unmatched Speed, Precision, and Security


Now Global Ecommerce and Digital Experience Leaders Can Access a Best-in-Class, Enterprise-Grade Personalization, Testing, and Optimization Platform


(BUSINESS WIRE) -- Monetate, the leading AI-driven personalization platform, today announced it has acquired SiteSpect, a leader in A/B testing, to drive next-generation digital experience optimization. This acquisition accelerates Monetate’s vision to deliver intelligent, intentional, and individualized experiences at scale, powered by agentic AI and backed by the industry’s most advanced, enterprise-grade infrastructure.


The combination of Monetate’s real-time personalization and SiteSpect’s zero-flicker testing will yield an industry-first solution for enterprise-grade personalization, testing, and optimization. For the first time, global ecommerce and digital experience leaders can access unified client-side and server-side experimentation with full personalization capabilities in a single solution, designed for scalability and regulatory compliance.


Monetate is now the only enterprise solution that can guide organizations through every stage of their digital experience journey with confidence, clarity, and creativity, according to Monetate CEO Steve Maher.


"We’re building the future of experience orchestration," said Maher. "With the combined strengths of Monetate and SiteSpect, we are tripling our combined engineering capacity while boosting the performance of our strategy consulting teams. This means faster innovation, more strategic guidance, and greater value for every customer, without compromising what makes each platform exceptional. It’s not just a leap forward for us; it’s an inflection point for the entire industry, and a huge win for our customers."


Monetate, a highly profitable, well-capitalized company, growing at over 30% annually, and backed by leading public and private investors with over $400 billion in assets under management, supports thousands of global blue-chip customers. The addition of SiteSpect’s patented technology, deep experience in private cloud and on-premise deployments, and enterprise-grade security, including HIPAA-ready and fully PCI-compliant solutions, will allow Monetate to expand into highly regulated sectors such as healthcare and financial services.


A Next-Generation Digital Optimization Platform


This acquisition yields a best-in-class solution for brands seeking a true enterprise-grade approach to experimentation and personalization. Existing customers will benefit from accelerated development, deeper expertise, and seamless support, while new customers gain immediate access to a powerful, AI-native platform purpose-built for scale and security.


Highlights of the unified solution include:


Hyper-Personalization at Scale – Every interaction shaped by real-time behavioral, contextual, and historical signals, powered by agentic AI and advanced product recommendations


Zero Flicker Experimentation – Client-side agility meets server-side power with latency-free, performance-grade testing


AI-Native Architecture – Designed from the ground up for transparency, security, and explainability; ideal for regulated industries


Mobile-Optimized Personalization – Tailored experiences delivered with speed, relevance, and consistency across every device


Omnichannel Reach – Seamless personalization across web, mobile, email, in-store, and customer care


Security-First, Enterprise-Grade – HIPAA-ready and fully GDPR and PCI compliant; built to exceed global standards for data protection


“This is not a retrofit—it’s a reinvention,” said Maher. “We’re bringing together two complementary technologies and teams to create a future-proof solution that will determine where digital experience optimization is going—instead of where it’s been.”


To learn more about this new chapter, visit www.monetate.com/sitespect.


About Monetate:


Monetate, the leading AI-driven personalization solution, delivers intelligent, intentional, and individualized digital experiences at scale, powered by agentic AI and backed by the industry’s most advanced, enterprise-grade infrastructure. Ecommerce and digital experience leaders rely on Monetate for next-generation digital experience optimization.


 


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Contacts

press@monetate.com

SS&C Blue Prism Recognized as a Gartner® Magic Quadrant™ RPA Leader for the Seventh Consecutive Year

 WINDSOR, Conn. - Monday, 30. June 2025



(BUSINESS WIRE) -- SS&C Technologies Holdings, Inc. (Nasdaq: SSNC) today announced that SS&C Blue Prism has been recognized as a Leader in the 2025 Gartner Magic Quadrant for Robotic Process Automation (RPA).


“We’re delighted SS&C Blue Prism has been named a Leader in the Gartner Magic Quadrant for Robotic Process Automation for the seventh year running,” said Bill Stone, CEO and Chairman of SS&C Technologies. “SS&C Blue Prism combines market-leading RPA and orchestration technologies with the latest artificial intelligence so organizations can tackle more complex tasks and dynamic business processes. We’ve scaled to more than 2,700 digital workers and AI agents across our own operations, resulting in over $200 million in annual savings. With SS&C leading the charge on deployment, customers can be confident in rolling out SS&C’s automation solutions securely, effectively, and responsibly.”


More than 2,800 companies worldwide leverage SS&C Blue Prism for AI-powered automation, helping organizations deliver their desired business outcomes across financial services, insurance, health and pharma, banking and more.


Download a complimentary copy of the report here for a deeper dive into 2025 Gartner Magic Quadrant for Robotic Process Automation.


With the right mix of proven technology, trusted partnerships, market-leading methodology and hands-on experience, SS&C Blue Prism helps highly regulated and complex businesses make agentic automation operational, not aspirational. Speak to an expert about SS&C’s offering.


About the Magic Quadrant


Gartner, Magic Quadrant for Robotic Process Automation, By Arthur Villa, Saikat Ray, Melanie Alexander, Sachin Joshi, 24 June 2025. GARTNER is a registered trademark and service mark of Gartner, Inc. and/or its affiliates in the U.S. and internationally, and MAGIC QUADRANT is a registered trademark of Gartner, Inc. and/or its affiliates and are used herein with permission. All rights reserved. Gartner does not endorse any vendor, product or service depicted in its research publications, and does not advise technology users to select only those vendors with the highest ratings. Gartner research publications consist of the opinions of Gartner's research organization and should not be construed as statements of fact. Gartner disclaims all warranties, expressed or implied, with respect to this research, including any warranties of merchantability or fitness for a particular purpose.


About SS&C Technologies


SS&C is a global provider of services and software for the financial services and healthcare industries. Founded in 1986, SS&C is headquartered in Windsor, Connecticut, and has offices around the world. More than 22,000 financial services and healthcare organizations, from the world's largest companies to small and mid-market firms, rely on SS&C for expertise, scale and technology.


SOURCE: SS&C


Additional information about SS&C (Nasdaq: SSNC) is available at www.ssctech.com.


Follow SS&C on X, LinkedIn and Facebook.


 


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Contacts

Brian Schell

Chief Financial Officer

SS&C Technologies

Tel: +1-816-642-0915

E-mail: InvestorRelations@sscinc.com


Justine Stone

Investor Relations

SS&C Technologies

Tel: +1- 212-367-4705

E-mail: InvestorRelations@sscinc.com


Media Contacts

Sam Gentile

Tel : +1-646-818-9195

Email : pro-SSC@prosek.com


 


 PREVIOUS POST

Altimetrik and SLK Software Join Forces to Create an AI-First Engineering Services Powerhouse


 DETROIT - 

(BUSINESS WIRE)--Altimetrik, a pure-play AI, Data and Digital engineering solutions company, today announced the signing of a definitive agreement to acquire SLK Software (“SLK”), a global technology services firm focused on delivering AI, intelligence automation and analytics solutions. The acquisition will further strengthen Altimetrik’s end-to-end enablement services and expand its customer reach, with a clear path to accelerate towards Altimetrik’s goal of reaching $1billion in annual revenue. The transaction remains subject to customary closing conditions and is expected to close in the second half of 2025. Financial details were not disclosed.


Founded in 2000, SLK is recognized as a leader in the tech industry, and for its commitment to create innovative digital solutions. This strategic acquisition will significantly enhance the scale of Altimetrik’s capabilities, bringing together Altimetrik’s AI-first, platform-native engineering model and SLK’s full technology services stack that will further accelerate the journey towards modernizing enterprise platforms for its customers.


Altimetrik is among the most evolved digital services providers with advanced data and digital engineering capabilities, a bite sized approach that creates high ROI client outcomes and exceptional track record of data and AI led deployments. Altimetrik will additionally leverage SLK’s deep customer relationships, global operational footprint and complementary leadership talent to further deliver innovation-led value creation for customers.


“In today’s world, AI, and especially Generative AI and Machine Learning, is the engine that is driving true business value,” said Raj Sundaresan, CEO of Altimetrik. “To enable an AI-First business a robust data cloud infrastructure that is grounded in product and platform engineering rigor is crucial. Our investment in SLK reflects our intention to deepen our commitment to customers who are looking for digital, AI-driven solutions that enable business value creation at unparalleled speed and scale. We are incredibly excited and look forward to welcoming SLK Software to the Altimetrik family.”


“This is not a traditional integration. It is a strategic acceleration,” said Parth Amin, Founder & Chairman of SLK Software. “In Altimetrik, we’ve found a partner who shares our values of customer intimacy, people centricity, and a passion for innovation and agility. Together we will unlock greater capabilities for our clients while preserving the speed and responsiveness they trust us for.”


Upon the closing of the transaction, the combined entity will serve a global customer base of over 150 businesses that include Fortune 500 companies and some of the most innovative tech enterprises. It will also enable a partnership network that includes era-defining pioneers such as OpenAI, Amazon Web Services, Snowflake, and Databricks. Together, the business will employ over 10,000 professionals around the world to support customers who are in their digital transformation journey and are looking for innovative solutions to modernize legacy systems through leveraging data and AI, while ensuring world-class governance, compliance, and platform security. This includes organizations across diverse industries, from Financial Services & Payments to Pharma and Lifesciences, to Technology and Manufacturing.


“Altimetrik and SLK coming together is a strategic leap for the industry,” said Puneet Bhatia, Co-Managing Partner and Country Head, India of TPG Capital Asia and Board Member at Altimetrik. “This combination creates an AI-first digital engineering platform with the scale, leadership, and execution muscle to deliver meaningful outcomes across industries. With TPG’s track record and experience in supporting enterprise tech businesses, we are proud to be able to support this next phase of growth and value creation.”


“This acquisition underscores TPG’s investment thesis in technology services, which is indexed on backing strategic technology providers that are leading the data and AI transformation journey for customers, with differentiated business, pricing and delivery models,” said Vivek Mohan, Business Unit Partner at TPG Capital Asia and Board Member at Altimetrik.


Highlighting the breadth and depth of the combined business, Raj Vattikuti, Board Member and Founder of Altimetrik said, “Beyond combining capabilities, bringing together the two businesses is about scaling what we do best: solving real business problems with precision and speed. With SLK, we are expanding our ability to bring industry context, simplify complexity, and deliver AI-native transformation.”


Ajay Kumar, CEO of SLK Software added, “SLK’s customer-first approach has led to building offerings powered by AI to deliver outstanding results for our clients. As a combined entity, SLK and Altimetrik are now set to unlock exceptional value and drive measurable impact at scale for our clients.”


Avendus Capital acted as the exclusive financial advisor to SLK Software. EY acted as the exclusive financial advisor to Altimetrik and TPG.


About Altimetrik


Altimetrik is a pure-play AI, Data, and Digital business services company. We focus on delivering business outcomes with an incremental, product-oriented approach. Our industry-first, proven digital business methodology provides a blueprint to develop, scale, and launch new products to market faster. Our team of 6,000+ practitioners with software, data, and cloud skills builds an agile engineering culture of collaboration and innovation that modernizes technology and builds new business models in bite-sized increments. As a strategic partner and catalyst, Altimetrik quickly delivers results without disruption. Recognized as a Major Contender in Everest Group’s BFSI IT Services Specialists PEAK Matrix® Assessment 2025 and a Product Challenger in ISG Provider Lens™ 2024 for Advanced Analytics and AI Services, Altimetrik continues to lead the way in delivering cutting-edge digital transformation. Learn more at altimetrik.com.


About SLK Software


SLK Software is a global technology services provider focused on bringing AI, intelligent automation, and analytics together to create leading-edge technology solutions for our customers through a culture of partnership with them, led by an evolutionary mindset. For 25 years, we have helped organizations across diverse industries — insurance providers, financial service organizations, investment management companies, and manufacturers — reimagine their business and solve their present and future needs. Certified as a Great Place To Work®, we encourage an approach of constructively challenging the status quo in all that we do to enable peak business performance for our customers and for ourselves, through disruptive technologies, applied innovation, and purposeful automation. Find out how we help leading organizations reimagine their business at www.slksoftware.com.


 


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Contacts

Media Contacts:


Altimetrik

Gurvinder Singh Sahni

GSahni@altimetrik.com


Matt McLoughlin

Gregory FCA on behalf of Altimetrik

altimetrik@GregoryFCA.com

+1 610-228-2123


SLK Software

Mohsina Faiz

mohsina.faiz@slksoftware.com

+91 8805008702


 

Monday, June 30, 2025

Takeda Announces U.S. FDA Approval of GAMMAGARD LIQUID ERC, the Only Ready-to-Use Liquid Immunoglobulin Therapy with Low Immunoglobulin A (IgA) Content1


 OSAKA, Japan & CAMBRIDGE, Mass. 

GAMMAGARD LIQUID ERC [immune globulin infusion (human)] with Less Than or Equal to 2 µg/mL IgA in a 10% Solution is Approved for Intravenous or Subcutaneous Use in People Aged Two and Older with Primary Immunodeficiency1

U.S. Commercialization of GAMMAGARD LIQUID ERC Projected to Begin in 2026

Company Announces Future Manufacturing Discontinuation End Date for Takeda's First-Generation Low-IgA Product, A Freeze-Dried Formulation in Company’s Differentiated Immunoglobulin Portfolio of Ready-to-Use Liquids2

(BUSINESS WIRE)--Takeda (TSE:4502/NYSE:TAK) today announced that the U.S. Food and Drug Administration (FDA) has approved GAMMAGARD LIQUID ERC [immune globulin infusion (human)] with less than or equal to 2 µg/mL IgA in a 10% solution, the only ready-to-use liquid immunoglobulin (IG) therapy with low immunoglobulin A (IgA) content, as replacement therapy for people two years of age and older with primary immunodeficiency (PI). As a ready-to-use liquid, GAMMAGARD LIQUID ERC may help ease the administration burden for patients and their health care providers by eliminating the need for reconstitution and can be administered intravenously or subcutaneously.1


“The approval of GAMMAGARD LIQUID ERC reinforces our commitment to supporting individualized treatment approaches for people with primary immunodeficiency, including a therapeutic option that has the lowest IgA content of any ready-to-use liquid immunoglobulin therapy, and can be administered intravenously or subcutaneously,” said Kristina Allikmets, senior vice president and head of Research & Development for Takeda’s Plasma-Derived Therapies Business Unit. “GAMMAGARD LIQUID ERC uses the same state-of-the-art manufacturing process as our other ready-to-use liquid immunoglobulin formulations and is aligned with our forward-looking strategy to prioritize reliable supply while offering a broad range of immunoglobulin therapies to address varied patient needs.”


With this approval, Takeda continues to be the only manufacturer of IG therapy with low IgA content less than or equal to 2 µg/mL in a 10% solution.1 It is anticipated that commercialization of GAMMAGARD LIQUID ERC will begin in the U.S. in 2026, followed by the European Union in 2027, where GAMMAGARD LIQUID ERC is approved by the European Medicines Agency (EMA) as DEQSIGA®.3 The timeline to commercial launch is consistent with the time it takes to ramp up manufacturing and supply for plasma-derived therapies.


In parallel to this approval, and after thorough analysis, Takeda has decided to discontinue GAMMAGARD S/D [Immune Globulin Intravenous (Human)] IgA less than 1 µg/mL in a 5% solution, the company’s first-generation low IgA product.2 As the only lyophilized (freeze-dried) preparation in Takeda’s IG portfolio, GAMMAGARD S/D uses a different, older manufacturing process. For GAMMAGARD S/D, this process is no longer able to reliably meet the future needs of the patient community. Therefore, Takeda has informed the FDA and other health authorities that manufacturing of GAMMAGARD S/D will be discontinued at the end of December 2027. Beyond that date, Takeda intends to maintain GAMMAGARD S/D inventory until it is depleted or expired.


“We understand the impact that this news may have on patients who currently rely on GAMMAGARD S/D for their treatment,” said Kristina Allikmets. “We are communicating this information now to allow time for patients to work closely with their health care teams to develop alternative treatment plans.”


About GAMMAGARD LIQUID ERC

GAMMAGARD LIQUID ERC is a ready-to-use liquid immunoglobulin therapy with an IgA content of less than or equal to 2 µg/mL in a 10% solution to be administered intravenously or subcutaneously. It is indicated in the United States as replacement therapy for primary immunodeficiency (PI) in people two years of age and older.1


GAMMAGARD LIQUID ERC shares its manufacturing process with GAMMAGARD LIQUID [Immune Globulin Infusion (Human)], with the modification of parameters in a single process step to improve IgA reduction. This enhanced removal capability (ERC) results in a product with IgA less than or equal to 2 µg/mL in a 10% solution.1


While GAMMAGARD LIQUID ERC is not indicated specifically for IgA sensitivity in people with primary immunodeficiency, it may be an appropriate option for them based on their physician’s clinical judgment. GAMMAGARD LIQUID ERC is contraindicated in patients with a history of severe systemic hypersensitivity or anaphylactic reactions to the product. It also carries warnings and precautions regarding the potential for severe hypersensitivity reactions, including in patients who have previously tolerated immune globulin products. Despite containing low levels of IgA (≤2 µg/mL in a 10% solution), the risk of anaphylaxis remains.1


About GAMMAGARD S/D

GAMMAGARD S/D is lyophilized (freeze-dried) immunoglobulin therapy with IgA content less than 1 µg/mL in a 5% solution for intravenous use only. It is indicated for the treatment of primary immunodeficiency (PI) in adults and pediatric patients 2 years and older. GAMMAGARD S/D is also indicated for prevention of bacterial infections in patients with hypogammaglobulinemia and/or recurrent bacterial infections associated with B-cell CLL, for the treatment of adult patients with chronic immune thrombocytopenic purpura (ITP) to increase platelet count and to prevent and/or to control bleeding, and for the prevention of coronary artery aneurysms associated with Kawasaki syndrome in pediatric patients.2


About Primary Immunodeficiency (PI)

Primary immunodeficiency (PI) is a group of more than 550 rare and chronic disorders, where a part of the body’s immune system is missing or does not function the way it should.4 These conditions result from genetic mutations, which are usually inherited.5 The symptoms of PI vary and can include frequent and/or persistent infections and unusual autoimmunity, often leading to prolonged periods of misdiagnosis despite consultations with multiple specialists.6 In the United States, PI affects about 1 in 1,200 people.7


GAMMAGARD LIQUID ERC, GAMMAGARD LIQUID and GAMMAGARD S/D U.S. Important Safety Information


WARNING: THROMBOSIS


Thrombosis may occur with immune globulin (IG) products, including GAMMAGARD LIQUID, GAMMAGARD LIQUID ERC and GAMMAGARD S/D. Risk factors may include advanced age, prolonged immobilization, hypercoagulable conditions, history of venous or arterial thrombosis, use of estrogens, indwelling vascular catheters, hyperviscosity, and cardiovascular risk factors. Thrombosis may occur in the absence of known risk factors.

For patients at risk of thrombosis, administer GAMMAGARD LIQUID, GAMMAGARD LIQUID ERC and GAMMAGARD S/D at the minimum dose and infusion rate practicable. Ensure adequate hydration in patients before administration.

Monitor for signs and symptoms of thrombosis and assess blood viscosity in patients at risk of hyperviscosity.

WARNING: RENAL DYSFUNCTION and ACUTE RENAL FAILURE


Renal dysfunction, acute renal failure, osmotic nephrosis, and death may occur in predisposed patients with immune globulin intravenous (IGIV) products, including GAMMAGARD LIQUID, GAMMAGARD LIQUID ERC and GAMMAGARD S/D. Patients predisposed to renal dysfunction include those with any degree of pre-existing renal insufficiency, diabetes mellitus, age greater than 65, volume depletion, sepsis, paraproteinemia, or patients receiving known nephrotoxic drugs. Renal dysfunction and acute renal failure occur more commonly in patients receiving IGIV products containing sucrose. GAMMAGARD LIQUID, GAMMAGARD LIQUID ERC and GAMMAGARD S/D do not contain sucrose.

Contraindications


GAMMAGARD LIQUID is contraindicated in patients with a history of anaphylactic or severe systemic hypersensitivity reactions to human IG, and IgA-deficient patients with antibodies to IgA and a history of hypersensitivity to human IG. Anaphylaxis has been reported with intravenous (IV) use of GAMMAGARD LIQUID.

GAMMAGARD LIQUID ERC and GAMMAGARD S/D are contraindicated in patients with a history of anaphylactic or severe systemic hypersensitivity reactions to the administration of GAMMAGARD LIQUID ERC and GAMMAGARD S/D.

Warnings and Precautions


Hypersensitivity: Severe hypersensitivity reactions may occur, even in patients who have tolerated previous treatment with human IG. Severe hypersensitivity reactions and anaphylactic reactions with a fall in blood pressure have occurred in patients receiving GAMMAGARD S/D, including patients who tolerated previous treatments with GAMMAGARD S/D, even though it contains low levels of IgA. If a hypersensitivity reaction occurs, discontinue infusion immediately and institute appropriate treatment. IgA-deficient patients with antibodies to IgA are at greater risk of developing potentially severe hypersensitivity reactions, including anaphylaxis.


Renal Dysfunction/Failure: Acute renal dysfunction/failure, acute tubular necrosis, proximal tubular nephropathy, osmotic nephrosis, and death may occur with IV use of IG products, especially those containing sucrose. Acute renal failure has been reported in association with GAMMAGARD LIQUID and GAMMAGARD S/D. Ensure patients are not volume depleted prior to infusion. In patients at risk due to pre-existing renal insufficiency or predisposition to acute renal failure, assess renal function before initiation and throughout treatment, and consider lower, more frequent dosing. If renal function deteriorates, consider discontinuation.


Hyperproteinemia, increased serum viscosity, and hyponatremia may occur. It is critical to distinguish true hyponatremia from pseudohyponatremia because certain treatments may lead to volume depletion, a further increase in serum viscosity, and a predisposition to thromboembolic events.


Thrombosis: Has been reported to occur following treatment with IG products and in the absence of known risk factors. In patients at risk, administer at the minimum dose and infusion rate practicable. Ensure adequate hydration before administration. Monitor for signs and symptoms of thrombosis and assess blood viscosity in patients at risk for hyperviscosity.


Aseptic Meningitis Syndrome: Has been reported with use of IG. Conduct a thorough neurological exam on patients exhibiting signs and symptoms, to rule out other causes of meningitis. Discontinuing IG treatment has resulted in remission within several days without sequelae. The syndrome usually begins within several hours to two days following IG treatment


Hemolysis: GAMMAGARD LIQUID, GAMMAGARD LIQUID ERC, and GAMMAGARD S/D contain blood group antibodies, which may cause a positive direct antiglobulin reaction and hemolysis. Monitor patients for signs and symptoms of hemolysis and delayed hemolytic anemia and, if present, perform appropriate confirmatory lab testing.


Transfusion-Related Acute Lung Injury: Non-cardiogenic pulmonary edema has been reported with IV-administered IG, including GAMMAGARD LIQUID. Monitor patients for pulmonary adverse reactions. If suspected, perform appropriate tests for presence of anti-neutrophil and anti-HLA antibodies in both product and patient serum. May be managed using oxygen therapy with adequate ventilatory support.


Transmittable Infectious Agents: Because GAMMAGARD LIQUID, GAMMAGARD LIQUID ERC, and GAMMAGARD S/D are made from human plasma, they may carry a risk of transmitting infectious agents (e.g., viruses, other pathogens). No confirmed cases of viral transmission or variant Creutzfeldt-Jakob disease (vCJD) have been associated with GAMMAGARD LIQUID.


Interference with Lab Tests: False positive serological test results and certain assay readings, with the potential for misleading interpretation, may occur as the result of passively transferred antibodies.


Alterations in serum sodium levels (i.e., acute hypernatremia, pseudohyponatremia) may occur with GAMMAGARD S/D. In patients on a low sodium diet, calculate the amount of sodium from GAMMAGARD S/D when determining dietary sodium intake.


Adverse Reactions


GAMMAGARD LIQUID


IV administration: The serious adverse reaction seen during IV clinical trials was aseptic meningitis. The most common adverse reactions observed in ≥5% of patients in clinical trials were headache, fatigue, pyrexia, nausea, chills, rigors, pain in extremity, diarrhea, migraine, dizziness, vomiting, cough, urticaria, asthma, pharyngolaryngeal pain, rash, arthralgia, myalgia, oedema peripheral, pruritus, and cardiac murmur.


Subcutaneous administration: The most common adverse reactions observed in ≥5% of patients in clinical trials were infusion site (local) event (rash, erythema, edema, hemorrhage, and irritation), headache, fatigue, heart rate increased, pyrexia, abdominal pain upper, nausea, vomiting, asthma, blood pressure systolic increased, diarrhea, ear pain, aphthous stomatitis, migraine, oropharyngeal pain, and pain in extremity.


GAMMAGARD LIQUID ERC


The safety of GAMMAGARD LIQUID ERC in patients with primary humoral immunodeficiency (PI) is supported by two clinical studies conducted on GAMMAGARD LIQUID. No clinical studies have been conducted using GAMMAGARD LIQUID ERC.


IV administration: The most common adverse reactions observed in ≥5% of patients in study 1 were headache, fatigue, pyrexia, chills, nausea, pain in extremity, diarrhea, migraine, vomiting, dizziness, urticaria, cough, asthma, oropharyngeal pain, infusion site extravasation, arthralgia, rash, myalgia, pruritis, and cardiac murmur.


Subcutaneous administration: The most common adverse reactions observed in ≥5% of patients in study 2 were infusion site (local) event, headache, pyrexia, fatigue, heart rate increased, abdominal pain upper, vomiting, arthralgia, nausea, asthma, blood pressure systolic increased, diarrhea, ear pain, aphthous ulcer, migraine, oropharyngeal pain, and pain in extremity.


GAMMAGARD S/D


The most common adverse reactions observed in ≥5% of clinical trial patients during or within 48 hours of infusion were headache, nausea, chills, fatigue, pyrexia, upper abdominal pain, diarrhea, back pain, infusion site pain, hyperhidrosis, and flushing.


The most serious adverse reactions reported postmarketing include renal failure, thrombotic events (myocardial infarction, cerebrovascular accidents, and pulmonary embolism), anaphylactic shock, aseptic meningitis, and hemolysis.


Drug Interactions


Passive transfer of antibodies may transiently interfere with the immune responses to live attenuated virus vaccines (e.g., measles, mumps, rubella, and varicella).


For Full U.S. Prescribing Information for GAMMAGARD LIQUID, please visit: https://www.shirecontent.com/PI/PDFs/GAMLIQUID_USA_ENG.pdf


For Full U.S. Prescribing Information for GAMMAGARD LIQUID ERC, please visit: https://content.takeda.com/?contenttype=PI&product=GAM&language=ENG&country=USA&documentnumber=2


For Full U.S. Prescribing Information for GAMMAGARD S/D, please visit: https://www.shirecontent.com/PI/PDFs/GGSD_USA_ENG.pdf


For European Union Summary of Product Characteristics for DEQSIGA, please visit: https://www.ema.europa.eu/en/medicines/human/EPAR/deqsiga


About Takeda

Takeda is focused on creating better health for people and a brighter future for the world. We aim to discover and deliver life-transforming treatments in our core therapeutic and business areas, including gastrointestinal and inflammation, rare diseases, plasma-derived therapies, oncology, neuroscience and vaccines. Together with our partners, we aim to improve the patient experience and advance a new frontier of treatment options through our dynamic and diverse pipeline. As a leading values-based, R&D-driven biopharmaceutical company headquartered in Japan, we are guided by our commitment to patients, our people and the planet. Our employees in approximately 80 countries and regions are driven by our purpose and are grounded in the values that have defined us for more than two centuries. For more information, visit www.takeda.com.


Important Notice

For the purposes of this notice, “press release” means this document, any oral presentation, any question and answer session and any written or oral material discussed or distributed by Takeda Pharmaceutical Company Limited (“Takeda”) regarding this release. This press release (including any oral briefing and any question-and-answer in connection with it) is not intended to, and does not constitute, represent or form part of any offer, invitation or solicitation of any offer to purchase, otherwise acquire, subscribe for, exchange, sell or otherwise dispose of, any securities or the solicitation of any vote or approval in any jurisdiction. No shares or other securities are being offered to the public by means of this press release. No offering of securities shall be made in the United States except pursuant to registration under the U.S. Securities Act of 1933, as amended, or an exemption therefrom. This press release is being given (together with any further information which may be provided to the recipient) on the condition that it is for use by the recipient for information purposes only (and not for the evaluation of any investment, acquisition, disposal or any other transaction). Any failure to comply with these restrictions may constitute a violation of applicable securities laws.


The companies in which Takeda directly and indirectly owns investments are separate entities. In this press release, “Takeda” is sometimes used for convenience where references are made to Takeda and its subsidiaries in general. Likewise, the words “we”, “us” and “our” are also used to refer to subsidiaries in general or to those who work for them. These expressions are also used where no useful purpose is served by identifying the particular company or companies.


Forward-Looking Statements

This press release and any materials distributed in connection with this press release may contain forward-looking statements, beliefs or opinions regarding Takeda’s future business, future position and results of operations, including estimates, forecasts, targets and plans for Takeda. Without limitation, forward-looking statements often include words such as “targets”, “plans”, “believes”, “hopes”, “continues”, “expects”, “aims”, “intends”, “ensures”, “will”, “may”, “should”, “would”, “could”, “anticipates”, “estimates”, “projects” or similar expressions or the negative thereof. These forward-looking statements are based on assumptions about many important factors, including the following, which could cause actual results to differ materially from those expressed or implied by the forward-looking statements: the economic circumstances surrounding Takeda’s global business, including general economic conditions in Japan and the United States; competitive pressures and developments; changes to applicable laws and regulations, including global health care reforms; challenges inherent in new product development, including uncertainty of clinical success and decisions of regulatory authorities and the timing thereof; uncertainty of commercial success for new and existing products; manufacturing difficulties or delays; fluctuations in interest and currency exchange rates; claims or concerns regarding the safety or efficacy of marketed products or product candidates; the impact of health crises, like the novel coronavirus pandemic, on Takeda and its customers and suppliers, including foreign governments in countries in which Takeda operates, or on other facets of its business; the timing and impact of post-merger integration efforts with acquired companies; the ability to divest assets that are not core to Takeda’s operations and the timing of any such divestment(s); and other factors identified in Takeda’s most recent Annual Report on Form 20-F and Takeda’s other reports filed with the U.S. Securities and Exchange Commission, available on Takeda’s website at: https://www.takeda.com/investors/sec-filings-and-security-reports/ or at www.sec.gov. Takeda does not undertake to update any of the forward-looking statements contained in this press release or any other forward-looking statements it may make, except as required by law or stock exchange rule. Past performance is not an indicator of future results and the results or statements of Takeda in this press release may not be indicative of, and are not an estimate, forecast, guarantee or projection of Takeda’s future results.


Medical Information

This press release contains information about products that may not be available in all countries, or may be available under different trademarks, for different indications, in different dosages, or in different strengths. Nothing contained herein should be considered a solicitation, promotion or advertisement for any prescription drugs including the ones under development.


References


____________________________

1 GAMMAGARD LIQUID ERC [immune globulin infusion (human)] with less than or equal to 2 µg/mL IgA in a 10% solution U.S. Prescribing Information.


2 GAMMAGARD S/D [Immune Globulin Intravenous (Human)] IgA less than 1 µg/mL in a 5% solution U.S. Prescribing Information.


3 European Medicines Agency. Deqsiga 100 mg/mL solution for infusion Summary of Product Characteristics. https://www.ema.europa.eu/en/medicines/human/EPAR/deqsiga


4 Immune Deficiency Foundation. Living With Primary Immunodeficiency. Accessed June 2025. Available at: https://primaryimmune.org/living-primary-immunodeficiency.


5 Center for Disease Control and Prevention. About Primary Immunodeficiency (PI). Accessed June 2025. Available at: https://www.cdc.gov/primary-immunodeficiency/about/index.html.


6 Immune Deficiency Foundation. Understanding Primary Immunodeficiency. Accessed June 2025. Available at: https://primaryimmune.org/understanding-primary-immunodeficiency.


7 Kobrynski L, Powell RW, Bowen S. J Clin Immunol. 2014;34(8):954-961.


 


 


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Contacts

Media Contacts:

U.S. Media

Taryn Corbino

Taryn.Corbino@Takeda.com

+1 (781) 915-9223


International Media

Kristine Kelly

Kristine.Kelly@takeda.com

+41 445551917


 

Thales 2025 Global Cloud Security Study Reveals Organizations Struggle to Secure Expanding, AI-Driven Cloud Environments

 MEUDON, France - Monday, 30. June 2025 AETOSWire 



52% report AI security spending is displacing traditional security budgets

55% report cloud environments are more complex to secure than on-premises infrastructure

Enterprises now use an average of 85 SaaS applications, contributing to security tool sprawl

 


(BUSINESS WIRE) -- Thales, a global leader in technology and cybersecurity, today released the findings of its 2025 Cloud Security Study conducted by S&P Global Market Intelligence 451 Research, revealing that AI-specific security has rapidly emerged as a top enterprise priority, ranking second only to cloud security. Over half (52%) of respondents said they are prioritizing AI security investments over other security needs, signaling a shift in how organizations are allocating budgets in response to the accelerated adoption of AI. This year’s research captures perspectives on cloud security challenges from nearly 3,200 respondents in 20 countries across a variety of seniority levels.


Cloud remains at the forefront of security considerations


Cloud is now an essential part of modern enterprise infrastructure, but many organizations are still building the skills and strategies needed to secure it effectively. The variability of controls across cloud providers, combined with the distinct mindset required for cloud security, continues to challenge security teams. This pressure is only increasing as AI initiatives drive more sensitive data into cloud environments, amplifying the need for robust, adaptable protections.


This year’s Thales Cloud Security Study confirms that cloud security remains a top concern for enterprises worldwide. Nearly two-thirds (64%) of respondents ranked it among their top five security priorities, with 17% identifying it as their number one. Security for AI, a new addition to the list of spending priorities this year, ranked second overall, highlighting its growing importance. Despite sustained investment, cloud security remains a complex, persistent challenge that goes beyond technology to include staffing, operations, and the evolving threat landscape.


“The accelerating shift to cloud and AI is forcing enterprises to rethink how they manage risk at scale,” Sebastien Cano, Senior Vice President, Cyber Security Products at Thales, said. “With over half of cloud data now classified as sensitive, and yet only a small fraction fully encrypted, it’s clear that security strategies haven’t kept pace with adoption. To remain resilient and competitive, organizations must embed strong data protection into the core of their digital infrastructure.”


The average number of public cloud providers per organization has risen to 2.1, with most also maintaining on-prem infrastructure. This growing complexity is driving security challenges with 55% of respondents reporting that cloud is harder to secure than on-prem, a 4-percentage-point increase from last year. As organizations expand through growth or M&A, they’re also seeing a surge in SaaS usage, now averaging 85 applications per enterprise, complicating access control and data visibility.


This complexity extends to security operations, with many teams struggling to align policies across varied platforms. The study found that 61% of organizations use five or more tools for data discovery, monitoring, or classification, and 57% use five or more encryption key managers.


Attacks target cloud resources with human error remaining a top vulnerability


Cloud infrastructure is a prime target for attackers as organizations continue to struggle with securing increasingly complex environments. According to the 2025 Thales Cloud Security Study, four of the top five most targeted assets in reported attacks are cloud-based. The rise in access-based attacks, as reported by 68% of respondents, underscores growing concerns around stolen credentials and insufficient access controls. Meanwhile, 85% of organizations say at least 40% of their cloud data is sensitive, yet only 66% have implemented multifactor authentication (MFA), leaving critical data exposed. Compounding the issue, human error remains a major contributing factor in cloud security incidents, from misconfigurations to poor credential management.


“A rising number of respondents report challenges in securing their cloud assets, an issue that is further amplified by the demands of AI projects that often operate in the cloud and require access to large volumes of sensitive data,” Eric Hanselman, Chief Analyst at S&P Global Market Intelligence 451 Research, said. “Compounding this issue, four of the top five targeted assets in reported attacks are cloud-based. In this environment, strengthening cloud security and streamlining operations are essential steps toward enhancing overall security effectiveness and resilience.”


For more information, please download the full report and join our webinar hosted by Eric Hanselman, Chief Analyst at S&P Global Market Intelligence 451 Research.


About Thales


Thales (Euronext Paris: HO) is a global leader in advanced technologies for the Defence, Aerospace, and Cyber & Digital sectors. Its portfolio of innovative products and services addresses several major challenges: sovereignty, security, sustainability and inclusion.


The Group invests more than €4 billion per year in Research & Development in key areas, particularly for critical environments, such as Artificial Intelligence, cybersecurity, quantum and cloud technologies.


Thales has more than 83,000 employees in 68 countries. In 2024, the Group generated sales of €20.6 billion.


PLEASE VISIT


Thales Group


Cloud Protection & Licensing Solutions | Thales Group


Cybersecurity Solutions | Thales Group


 


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Contacts

PRESS


Thales, Media Relations

Security & Cybersecurity

Marion Bonnet

+33 (0)6 60 38 48 92

marion.bonnet@thalesgroup.com