Tuesday, June 30, 2026

Cartilage Tissue Engineering Heads to Orbit in NSF and NASA-supported Study at the International Space Station

 


SEATTLE - 

UC Irvine researchers use single cell RNA sequencing to study cartilage tissue engineered in microgravity


(BUSINESS WIRE) -- Researchers in the DELTAi Lab at the University of California, Irvine, working with NASA, are using Evercode Cell Fixation to preserve samples aboard the International Space Station as part of a study of cartilage tissue engineering in microgravity. The unprecedented work, part of a National Science Foundation (NSF)-funded grant led by Dr. Wendy Brown and Dr. Kyriacos Athanasiou, announced today by Parse Biosciences, aims to advance treatments for the hundreds of millions of people worldwide affected by cartilage injury.


Cartilage injuries cause significant pain and disability, and the need for implants that can repair or regenerate damaged tissue without harming a donor site has gone unmet for decades. Part of the difficulty is gravity itself, which may work against the formation of cartilage tissue in the lab. Microgravity may help get around that problem, and a growing line of research suggests that tissues engineered in orbit can come closer to the real thing than tissues engineered on the ground.


The researchers at UC Irvine first rejuvenate highly expanded chondrocytes to restore chondrogenic gene expression and the cells’ ability to produce cartilage. The cells are then allowed to self-assemble into neocartilage without a scaffold, and the tissue is matured under mechanical tension to build up its strength. All of this takes place in orbit in flight-certified hardware developed by BioServe Space Technologies at the University of Colorado Boulder, with samples taken for study at timepoints from the first hours of differentiation to nearly 30 days of neocartilage culture. The samples are preserved with Parse Biosciences' Evercode Cell Fixation and returned to Earth for single cell RNA sequencing.


According to Dr. Rachel Nordberg, who is leading the study to examine the rejuvenation of these cells, “The ability to study rejuvenation of our minipig cells in microgravity at the single cell level requires us to be able to effectively preserve the cells with a long storage timeframe. We also need a species-agnostic platform that has full functionality with our specialized animal model (the Yucatan minipig).” Dr. Wendy Brown added, “Parse offers the perfect solution to give us the flexibility we need to study minipig cells, collect samples at multiple timepoints, and handle the unpredictability of spaceflight operations.”


“What the UC Irvine team is doing is remarkable. Engineering cartilage in microgravity could fundamentally change how we think about tissue repair, and the fact that they are running this level of single cell work from samples preserved in orbit is a real testament to the rigor of their science. We are honored that Evercode is a small part of it,” said Charlie Roco, PhD, Co-founder and Chief Technology Officer at Parse Biosciences.


About Parse Biosciences


Parse Biosciences, a QIAGEN company, is a global life sciences company whose mission is to accelerate progress in human health and scientific research. Empowering researchers to perform single cell sequencing with unprecedented scale and ease, its pioneering approach has enabled groundbreaking discoveries in cancer treatment, tissue repair, stem cell therapy, kidney and liver disease, brain development, and the immune system.


 


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Contacts

Kaitie Kramer

kkramer@parsebiosciences.com | +1-858-504-0455


 

MANE Selects Kinaxis to Strengthen Global Planning Capabilities

 Kinaxis Maestro™ platform to provide the digital foundation to strengthen MANE’s global planning capabilities and support its continued planning transformation


(BUSINESS WIRE) -- Kinaxis® (TSX:KXS), a global leader in end-to-end supply chain planning and orchestration, today announced that MANE, one of the top five leading organizations worldwide in the flavours and fragrances industry, has selected Kinaxis to modernize its planning capabilities as it accelerates global growth as part of a broader enterprise-wide transformation initiative.


Headquartered in the south of France, with a significant global footprint spanning multiple regions and customers across international markets, MANE is known for its innovation, technical expertise and strong commitment to sustainability. The company is investing in more connected, end-to-end planning capabilities to support continued growth and increasing operational complexity worldwide.


Following an extensive evaluation process with major competitors in the market, MANE selected the Kinaxis Maestro platform for its proven ability to support complex, multi‑region planning environments with speed, transparency, and confidence. Unlike legacy systems that rely on static data and sequential processes, Maestro allows teams to instantly see the impact of change, run scenarios in real time, and make faster, more informed decisions.


“Kinaxis offered the modern architecture and flexibility we were looking for to support our rapid transformation,” said Scott Quinn, ERP Program Director at MANE. “We needed an AI-driven solution that could scale alongside our global footprint, support our teams across regions, and provide a single, reliable view of demand as we continue to grow.”


With Maestro, MANE will gain AI-powered demand planning built on a concurrent data model, enabling teams to instantly assess change and align demand decisions across functions while providing the foundation to replace static, fragmented planning processes with a more agile and responsive approach.”


“MANE’s rapid global expansion brings a new level of planning complexity, from sourcing natural raw materials and managing increasingly interconnected supply networks to meeting the needs of customers across diverse regional markets,” said Mark Morgan, President of Global Commercial Operations at Kinaxis. “Navigating this level of complexity requires a fundamentally different approach to planning, and MANE is demonstrating that kind of forward-thinking leadership having selected Kinaxis to provide the orchestration capabilities needed to support their next phase of growth. With Maestro as their foundation, MANE will be better positioned to anticipate change, align decisions across the business and scale with confidence. We’re excited to support them in this next chapter.”


MANE is taking a phased approach to its supply chain transformation with the initial deployment focused on demand planning and future expansion of Maestro anticipated as the company continues to scale. To learn more about Kinaxis and its industry‑leading supply chain orchestration platform visit www.kinaxis.com.


About Kinaxis


Kinaxis is a leader in modern supply chain planning and orchestration, powering complex global supply chains, and supporting the people who manage them. Our powerful, AI-infused supply chain orchestration platform, Maestro, combines proprietary technologies and techniques that provide full transparency and agility across the entire supply chain — from multi-year strategic planning to last-mile delivery. We are trusted by renowned global brands to provide the agility and predictability needed to navigate today’s volatility and disruption. For more news and information, please visit kinaxis.com or follow us on LinkedIn.


Source: Kinaxis Inc.


 


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Contacts

Media Relations

Erin Boyle | Kinaxis

eboyle@kinaxis.com

+1 519-574-4065


Investor Relations

Victoria Hyde-Dunn | Kinaxis

vhyde-dunn@kinaxis.com

Esri Sponsors Smithsonian Exhibition Showcasing Natural and Cultural Objects from All 50 States


 REDLANDS, Calif. - 

From These Lands Exhibition Highlights Connections Between People, Place, and Natural World Through Physical Specimens and Digital Maps


Esri is the lead sponsor of the Smithsonian's From These Lands exhibition and developed maps powered by ArcGIS and a digital companion to extend engagement beyond the museum.

The exhibition features more than 600 specimens and cultural artifacts from all 50 states, Washington, DC, and US territories, drawn from the Smithsonian's National Museum of Natural History's collection of over 148 million objects.

Designed around themes of connection, diversity, and discovery, the exhibit explores how landscapes, ecosystems, and cultural traditions shape one another across regions and time.

Animated mapping experiences enable visitors to explore topography, biomes, geology, migration patterns, and watersheds, revealing relationships across the continent.

ArcGIS StoryMaps transforms the physical exhibit into an accessible digital narrative, extending its reach to educators, students, and global audiences.

 


(BUSINESS WIRE) -- Esri, the global leader in location intelligence, is sponsoring From These Lands: Sharing Our Natural and Cultural Heritage, a new exhibition at the Smithsonian's National Museum of Natural History that showcases objects from all 50 states and explores the deep connections between people, place, and the natural world that unite the nation.


The exhibit, which opened this June 18 and runs through 2029, brings together more than 600 specimens and cultural artifacts from across the United States, Washington, DC, and the five territories that people call home. Drawing from the museum's own collection, From These Lands shows how natural systems, cultural traditions, and geography intersect.


The exhibition presents stories that span millions of years—from ancient fossils and geological formations to cultural artifacts and scientific breakthroughs—inviting visitors to reflect on their own sense of place. By pairing natural specimens with cultural objects, From These Lands demonstrates how human cultures are both shaped by and actively shape the natural world.


Esri's technology plays a central role in bringing these themes to life. Animated maps within the gallery allow visitors to explore North America through geographic lenses such as topography, biomes, geology, migration routes, and watersheds, helping reveal patterns and relationships across landscapes.


The Smithsonian collaborated with Esri to create a companion story that extends the new exhibition into a dynamic digital experience. The ArcGIS StoryMaps story integrates maps, multimedia, and narrative content to connect objects and stories across locations, effectively transforming the exhibit into a living, interactive resource that can be accessed from anywhere.


"We are honored and thrilled to make this contribution to such an enriching exhibit at the Smithsonian showcasing the nation's natural history," said Jack Dangermond, Esri president. "The immersive experience of the museum's artifacts and animated maps emphasize how our shared geography connects us even across great distances and boundaries."


Visitors can experience From These Lands: Sharing Our Natural and Cultural Heritage at the Smithsonian's National Museum of Natural History in Washington, DC, and explore the story online.


About Esri


Esri, the global market leader in geographic information system (GIS) software, location intelligence, and mapping, helps customers unlock the full potential of data to improve operational and business results. Founded in 1969 in Redlands, California, USA, Esri software is deployed in hundreds of thousands of organizations globally, including Fortune 500 companies, government agencies, nonprofit institutions, and universities. Esri has regional offices, international distributors, and partners providing local support in over 100 countries on six continents. With its pioneering commitment to geospatial technology and analytics, Esri engineers the most innovative solutions that leverage a geographic approach to solving some of the world's most complex problems by placing them in the crucial context of location. Visit us at esri.com.


Copyright © 2026 Esri. All rights reserved. Esri, the Esri Globe logo, ArcGIS, The Science of Where, esri.com, and @esri.com are trademarks, service marks, or registered marks of Esri in the United States, the European Union, or certain other jurisdictions. Other companies and products or services mentioned herein may be trademarks, service marks, or registered marks of their respective mark owners.


 


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Contacts

media.help@esri.com

Geoswift and SKUx Announce Strategic Partnership to Develop a First-of-Its-Kind Programmable Stablecoin Commerce Network


 VANCOUVER, British Columbia & ST. PETERSBURG, Fla. 

Bridging digital assets, traditional finance, enterprise treasury, and agentic commerce through global programmable money infrastructure


 


(BUSINESS WIRE)--Geoswift and SKUx announced a groundbreaking partnership to develop a next-generation programmable stablecoin commerce network. This strategic collaboration bridges digital assets, traditional finance, and real-world commerce at a global scale, representing a "one-of-one" opportunity by combining Geoswift's global infrastructure with SKUx's specialized item-level controls directly within point-of-sale (POS) systems.


While enterprise stablecoin usage continues to accelerate globally, governments, enterprises, payment networks, and AI-driven commerce platforms are increasingly seeking programmable payment infrastructure that can bridge digital assets with real-world commerce. The innovation goes far beyond treasury management or even enabling consumers to spend stablecoins at retail locations. Instead, it unlocks true "programmable money" with embedded controls, rules, and purpose-driven utility —requiring both programmable settlement and programmable spending controls. Geoswift and SKUx are uniquely positioned to achieve this by pairing Geoswift’s global payment network, stablecoin settlement capabilities, liquidity support, and compliance infrastructure with SKUx’s multi-patented offers platform and extensive item-level partner network.


Global Infrastructure and Enhanced Merchant Compliance. Designed to be adaptable to any retailer environment, SKUx’s SKUPay® technology is already embedded in an estimated 50% of major U.S. grocery and big-box point-of-sale systems, unlocking a significant new category of merchant payment infrastructure. While the initial launch is U.S.-focused, the partnership builds on Geoswift’s proven global network and cross-border scale, following its recent integrations with Visa Direct and the Circle Payments Network. Spanning 140+ countries and 110+ payout currencies, Geoswift's footprint enables seamless international expansion and robust transaction compliance. Through its global banking and payment infrastructure, Geoswift processes cross-border transactions for enterprises, financial institutions, education providers, e-commerce platforms, and global merchants. By merging item-level payment precision with global stablecoin settlement transparency, the network opens entirely new programmable applications across retail, healthcare, government benefits, and cross-border commerce.


Beyond these commerce use cases, the network will also enable enterprise treasury programs that leverage stablecoin infrastructure to improve liquidity management, settlement efficiency, and working capital utilization.


Guardrails for Agentic Commerce. As the landscape shifts toward AI-driven agentic commerce—where autonomous AI agents execute financial workflows—securing the merchant control layer is paramount. While global payment networks are actively building authorization and settlement layers, a critical gap remains in validating exactly “what” automated agents are purchasing. This partnership solves that gap, delivering the specific item-level guardrails required to accept automated, programmable purchases securely and transparently.


"Stablecoins have solved for programmable settlement. SKUx and Geoswift are now solving for programmable spending," said Raymond Qu, Group CEO and founder of Geoswift. "Together, we are creating the infrastructure that enables digital assets, AI agents, enterprises, and consumers to transact securely in the real economy at global scale."


"By anchoring Geoswift's global liquidity and compliance engine directly into our platform infrastructure, we are transforming how the world views digital assets at the point of sale," said Bobby Tinsley, CEO and co-founder of SKUx. "This isn't just about enabling payments—it's about bringing unprecedented item-level intelligence and security to the next generation of global commerce, including the rapidly emerging world of autonomous AI agents."


The long-term vision of the partnership is to enable purpose-bound digital money that can be programmed with rules, spending controls, compliance requirements, and settlement instructions across global commerce networks.


About Geoswift


Geoswift is an innovative global payment technology company specializing in APAC cross-border payments. Since its founding in 2010, the Geoswift brand has become synonymous with proprietary innovation, deep expertise in international and local regulatory frameworks, robust banking partnerships, and a strong global presence. Licensed in the United States, United Kingdom, and Hong Kong SAR—and supported by an extensive payment network spanning APAC, North America, EMEA and Latin America—Geoswift provides customized, end-to-end cross-border payment solutions for a broad spectrum of industries, including education, e-commerce, travel, and financial services.


Its comprehensive product suite includes payment acceptance, business payouts, foreign exchange, multi-currency business accounts, card solutions, and more. Headquartered in Vancouver, Canada, Geoswift has regional offices in Hong Kong, San Francisco, London and Singapore—offering seamless, localized payment solutions to clients across the globe. For more information, visit geoswift.com.


About SKUx


SKUx provides a purpose-driven network that combines easy mobile wallet delivery with granular transaction controls. Their platform allows brands to bypass legacy coupon systems and replace them with secure, digital payments that can be restricted by merchant category, location and all the way down to the SKU-level. This item-level precision helps eliminate fraud and waste while providing brands with 360-degree visibility into how funds are used in real-time. For more information, visit skux.io.


 


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Contacts

 

Media Contact:

Brenda Ng

Geoswift Media Contact

Brenda.ng@geoswift.com


Reva Henderson

SKUx Media Contact

Will Marlow Agency

+1 727-580-1910

reva@willmarlow.com


 

Monday, June 29, 2026

The Premier Jumping League (PJL) & McCarthy Jumping Team Announce Landmark Purchase

 With $50 Million Team Acquisition, McCarthy Jumping Team Becomes First PJL Ownership Group


Acquisition illustrates strong investor confidence in the future of professional showjumping as highly anticipated 2027 inaugural season to feature 16 teams competing across 14 international events

(BUSINESS WIRE) -- The Premier Jumping League (PJL) today announced that seasoned trader, investor, and competitive race car driver Jason McCarthy and McCarthy Jumping League LLC acquired the first PJL team in a landmark $50 million acquisition, building on rising momentum for the highly acclaimed professional jumping league.

The milestone investment represents an unprecedented valuation for a team in a newly established sports competition and underscores the confidence that sophisticated investors are placing in the PJL.

The inaugural PJL season is scheduled to commence in April 2027.

McCarthy brings extensive investment and trading experience to the League, having held leadership positions across the financial sector throughout his career. A graduate of MIT, McCarthy is the Founder and Managing Principal of a proprietary trading firm active across a diverse range of domestic and international markets. He, his wife, Newsha, and their daughter, Natalia, share a deep passion for horses, owning equine farms in Watermill, NY and Wellington, FL. Natalia is a junior competitive rider who aspires to one day compete at the highest level of jumping.

The McCarthy Jumping Team acquisition reflects confidence in McCourt Global’s $300 million prize money commitment, and in the long-term vision, business model, and financial viability of the PJL. Through a disciplined focus on expanding the commercial potential of jumping, the PJL is establishing itself as an investable sports property, with a clear pathway to long-term asset appreciation.

Commenting on the investment, McCarthy said: “Like Frank McCourt, our family's journey into this sport began with my wife, Newsha, whose lifelong love of horses first introduced us to the equestrian world. Through her passion, we became fans of jumping and developed a deep appreciation for the extraordinary partnership between horse and rider.

We believe strongly in the PJL’s vision – a league committed to the highest ethical standards, meritocracy, and elite competition, underpinned by a sustainable commercial model that attracts the world’s best riders and delivers fan experiences on par with the greatest global sporting competitions.

We see enormous potential for the sport to grow its global audience while remaining true to the values that make it so special. We are confident the PJL will help realise that potential and drive meaningful growth for the sport we have come to love.”

Executive Chairman of McCourt Global, Frank McCourt, added: “This investment is a powerful endorsement of the PJL’s vision and the future potential of jumping. From the outset, our ambition has been to attract new capital and new growth opportunities to the sport. Jason and his family embody the values and ethos we aim to uphold within the League, and we are delighted to welcome McCarthy Jumping Team as the PJL’s first ownership group.”

About the Premier Jumping League (PJL)

The PJL is a groundbreaking global 16-team competition defining a new era for showjumping.

Backed by McCourt Global and its Executive Chairman Frank McCourt, and shaped by leaders from equestrian sport, international competition, and entertainment, the PJL brings together the world’s top riders and horses to compete for the biggest prize pot in the discipline’s history ($300M guaranteed prize money across the first three years), across fourteen iconic venues in North America, Europe, and the Middle East.

Designed to open the sport to new audiences whilst respecting its heritage, the PJL combines extraordinary athletic performance with premium entertainment, strengthened by the league’s partnership with Box to Box Films (the production company behind F1’s ‘Drive to Survive’), and supported by a free-to-view broadcasting model.

Cutting-edge technology, radical transparency, and innovative team formats enhance the drama, intensity, and rivalry that define elite sport – unlocking the full potential of jumping, demanded by today’s global sports and entertainment marketplace, without compromising its core values.

The PJL distinguishes itself through its commitment to the highest standards of horse and rider welfare.

The PJL continues to work closely with the FEI as the League progresses through the Series Approval process. A decision is expected imminently.

About the McCarthy Jumping Team

McCarthy Jumping Team is privately held by the McCarthy Family Office, which services the interests of the McCarthy family.

 

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Contacts
Kelly Hogarth | pressoffice@pjl.com | [+44 777 269 7805]
Follow The PJL:
Website: www.pjl.com
Substack: @thepjl
Instagram: @the_pjl_official

Mastercard launches Africa Cybersecurity Center of Excellence to help secure the continent's digital future

 Johannesburg, South Africa - Monday, 29. June 2026 AETOSWire Print 



 


New pan-African initiative aimed at strengthening collective cyber resilience across Africa's digital economy

Brings together public and private sector organizations to share intelligence, build readiness and support improved response

Launch begins in South Africa and Nigeria, reinforcing Mastercard's long-term commitment and investments in Africa's digital transformation and supporting trust in the digital ecosystem

 


Mastercard announced the launch of its Africa Cybersecurity Center of Excellence, a pan-African initiative designed to strengthen cyber resilience, enhance collaboration and help safeguard the trust that underpins Africa's expanding digital economy.


The announcement was made during a visit to South Africa and Nigeria by Mastercard CEO, Michael Miebach, reflecting Mastercard's long-term commitment to supporting Africa's digital transformation by helping organizations anticipate, withstand and recover from increasingly sophisticated cyber threats. The Cybersecurity Center of Excellence extends Mastercard’s expertise and network, bringing global competence and intelligence to one of the world's fastest-growing digital economies.


This initiative follows through on commitments made in recent discussions with the Nigerian Government in Abuja, and the South African Government during last year’s G20 meetings in Johannesburg, to strengthen cybersecurity efforts in Africa.


His Excellency, Cyril Ramaphosa, President of South Africa, said: “We recognize that for digitization to be inclusive, it must be trusted and secure. Mastercard has long been a trusted partner to South Africa, and its Cybersecurity Centre of Excellence is a welcome step to build on that foundation, drawing on the country’s best and brightest to meet a challenge no government or company can solve alone."


His Excellency, Bola Ahmed Tinubu, GCFR, President of Nigeria, said: “As Nigeria deepens its digital transformation, secure and trusted systems will be critical to inclusion and growth. We welcome collaborations that strengthen our digital economy and build resilience for the future.”


As digital adoption accelerates across Africa, cybersecurity has become an imperative for economic growth. No single organization can face today’s cyber threats alone. The Africa Cybersecurity Center of Excellence has been established to support the strengthening of collective defense across the continent by bringing together financial institutions, public sector organizations and businesses to share intelligence, improve preparedness, anticipate threats earlier and build resilience over time.


Michael Miebach, CEO, Mastercard, said: "Africa is dynamic, fast-growing, and ready to scale its digital future. That won't happen without trust. People don't use what they don't trust. That makes cybersecurity foundational to driving economic resilience and growth across the continent. By doing more to connect public and private sector efforts and share best practices, we can strengthen collective defense and secure a more confident and inclusive digital economy." 


As Africa’s digital economy is projected to reach $1.5 trillion by 2030, the need for greater collaboration has never been more urgent. Cybercrime across Africa is rising sharply, resulting in significant economic losses each year, with only an estimated 35% of incidents officially reported. This underreporting is driven by cyber maturity gaps, limited detection capabilities, and reputational concerns, thus creating a fragmented view of the threat landscape and weakening coordinated response efforts across the region. South Africa is the continent’s most targeted market, accounting for around 29% of ransomware attacks and 40% of phishing incidents in Africa, while Nigeria ranks among the most affected markets for ransomware and dark-web threat activity.


The multi-year initiative will be led by Mastercard. It will begin a phased rollout in 2026, starting with South Africa and Nigeria. Through this collective model, it is intended to support the strengthening of cyber resilience and preparedness and enable more secure digital growth across Africa.


Operating as a pan‑African hub delivered through connected digital platforms and capabilities, the Center will help participating organisations gain greater visibility into emerging threats. This includes a first‑year ecosystem cyber risk analysis covering up to 50 organisations, alongside access to an Africa‑focused threat intelligence feed developed by Recorded Future, a Mastercard company. Through collaboration among CISOs, business leaders and security practitioners - enabled by secure information‑sharing, joint exercises and coordinated response - the Center will strengthen a more connected and resilient cybersecurity ecosystem across Africa.


The Center of Excellence is designed to evolve over time, expanding its capabilities as market needs develop. At the heart of the initiative are three core pillars:


Threat intelligence & strategic insights: Providing participating organizations with Africa-focused threat intelligence, including cybersecurity intelligence assessments across Africa and a shared view of risks.

Collaboration & knowledge sharing: Bringing together CISOs, senior business leaders and security teams to support enhanced collective response capabilities and advance cybersecurity best practices across industries.

Readiness & resilience: Helping organizations anticipate emerging threats through ongoing risk monitoring, resilience assessments, and scenario-based exercises designed to strengthen response and recovery capabilities.

 


The launch of the Africa Cybersecurity Center of Excellence represents the next chapter in Mastercard's broader mission to build trust in the digital economy. The company has invested more than $12.6 billion in cybersecurity innovation since 2018 and has supported the launch of more than 20 cybersecurity-focused startups. This marks a further step in Mastercard’s evolution from a payments network to a trusted technology and cyber intelligence partner, supporting the strengthening of cyber resilience across Africa and enabling secure, inclusive and sustainable digital growth.


By working alongside governments, financial institutions and businesses of all sizes, including SMEs, Mastercard intends to help strengthen the digital foundations that underpin inclusive growth.  By investing in capabilities that address the continent’s evolving realities, Mastercard seeks to support the development of a more secure and resilient digital future across the markets in which it operates.


About Mastercard

Mastercard powers economies and empowers people in 200+ countries and territories worldwide. Together with our customers, we’re building a resilient economy where everyone can prosper. We support a wide range of digital payments choices, making transactions secure, simple, smart and accessible. Our technology and innovation, partnerships and networks combine to deliver a unique set of products and services that help people, businesses and governments realize their greatest potential. www.mastercard.com



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Contacts

Troy Mocheko


Troy.Mocheko@mastercard.com


Samsung Bioepis Announces Positive Preliminary Phase 1 and Phase 3 Data for SB27, a Proposed Biosimilar to Keytruda (Pembrolizumab)

INCHEON, Korea - Monday, 29. June 2026 AETOSWire  


Phase 1 study demonstrated pharmacokinetic (PK) equivalence between SB27 and Keytruda; Phase 3 study demonstrated equivalent objective response rate (ORR) at Week 24

Phase 1 and Phase 3 studies expected to be completed within 2026

 


(BUSINESS WIRE) -- Samsung Bioepis Co., Ltd. announced today that the Phase 1 and Phase 3 studies on SB27, a proposed biosimilar to Keytruda1 (pembrolizumab), have met their primary endpoints.


“We are excited to announce preliminary results from the Phase 1 and Phase 3 studies for SB27, our pembrolizumab biosimilar candidate. These topline positive results reinforce our scientific expertise and leadership in biosimilar development,” said Donghoon Shin, Executive Vice President and Head of Clinical Sciences Division at Samsung Bioepis. “We are on track to complete both Phase 1 and Phase 3 studies within this year. Leveraging our robust quality management system, we remain committed to advancing our biosimilar portfolio to broaden access to life-saving biologic medicines for patients with unmet needs.”


Pembrolizumab is a humanized monoclonal antibody that acts as an immune checkpoint inhibitor by targeting and blocking the programmed cell death protein 1 (PD-1) receptor on T cells. It is used to treat various types of cancer, including melanoma, non-small cell lung cancer (NSCLC), and head and neck squamous cell cancer (HNSCC).2


The randomized, double-blind, three-arm, parallel group, multicenter Phase 1 clinical trial demonstrated pharmacokinetic (PK) bioequivalence of SB27 (pembrolizumab) to the reference product Keytruda. The study assessed PK, efficacy, safety, and immunogenicity of SB27, EU-sourced Keytruda, and US-sourced Keytruda in patients with stage II or IIIA NSCLC following complete resection and adjuvant platinum-based chemotherapy.3 163 participants were randomized to receive SB27, EU-sourced Keytruda, or US-sourced Keytruda every 3 weeks up to 51 weeks, and blood samples were collected. The preliminary PK evaluation indicates that the drug exposure, measured by the Area Under the Curve (AUC), has met the predefined equivalence criteria.


The randomized, double-blind, parallel group, multicenter Phase 3 clinical trial demonstrated equivalent objective response rate (ORR) at Week 24. The study assessed efficacy, safety, PK, and immunogenicity of SB27 and Keytruda in patients with metastatic non-squamous NSCLC, followed by chemotherapy.4 555 participants were randomized to receive SB27 or Keytruda followed by pemetrexed and carboplatin5 every 3 weeks up to 48 weeks. The 90% confidence interval (CI) for the ORR ratio between SB27 and Keytruda at Week 24 was 0.737 to 1.071, which completely fell within the pre-defined equivalence margin of 0.712 to 1.405, thereby demonstrating equivalence. Safety, PK and immunogenicity profiles of SB27 were also comparable with those of Keytruda.


About Samsung Bioepis Co., Ltd.


Established in 2012, Samsung Bioepis is a biopharmaceutical company committed to realizing healthcare that is accessible to everyone. Through innovations in product development and a firm commitment to quality, Samsung Bioepis aims to become the world's leading biopharmaceutical company. As a wholly owned subsidiary of Samsung Epis Holdings, Samsung Bioepis continues to advance a broad pipeline of biologic candidates that cover a spectrum of therapeutic areas, including immunology, oncology, ophthalmology, hematology, nephrology, endocrinology and neurology. For more information, please visit www.samsungbioepis.com and follow us on LinkedIn and X.


 


 


1 Keytruda is a trademark of Merck Sharp & Dohme LLC


2 European Medicines Agency (EMA). Keytruda Summary of Product Characteristics (SmPC). Available at: https://www.ema.europa.eu/en/documents/product-information/keytruda-epar-product-information_en.pdf Last accessed June 2026.


3 ClinicalTrials.gov (NCT06268613). A Study to Compare the Pharmacokinetics, Efficacy, Safety, and Immunogenicity of Pembrolizumab (SB27, EU Sourced Keytruda, and US Sourced Keytruda) in Subjects With Stage II-IIIA NSCLC Following Complete Resection and Adjuvant Platinum-based Chemotherapy. Available at: https://clinicaltrials.gov/study/NCT06268613 (Accessed June 2026)


4 ClinicalTrials.gov (NCT06348199). A Study to Compare the Efficacy, Safety, Pharmacokinetics, and Immunogenicity Between SB27 and Keytruda in Subjects With Metastatic Non-squamous Non-small Cell Lung Cancer. Available at: https://clinicaltrials.gov/study/NCT06348199 (Accessed June 2026)


5 Carboplatin was administered for the first four cycles.


 


 


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Contacts

Media Contact

Anna Nayun Kim, nayun86.kim@samsung.com

Yoon Kim, yoon1.kim@samsung.com

Medisca Enters Its Next Chapter Under Founder Antonio Dos Santos

MONTREAL - Monday, 29. June 2026


Medisca today announced that Founder and Chairman Antonio Dos Santos has returned to the role of Chief Executive Officer as the company enters its next chapter of growth.


(BUSINESS WIRE) -- For more than 35 years, Dos Santos has helped shape Medisca into a global leader in pharmaceutical compounding. As Chief Executive Officer, he will lead the company's long-term strategy, with a focus on expanding Medisca's global reach, investing in new areas of growth, strengthening strategic partnerships, and continuing to advance the products, services, education, and expertise that healthcare professionals rely on every day.


"When I founded Medisca, my vision was to raise the standard of pharmaceutical compounding by bringing pharmaceutical-grade quality to the industry and giving healthcare professionals access to the products, knowledge, and innovation they needed to deliver better patient care," said Antonio Dos Santos, Founder and Chief Executive Officer of Medisca. "That purpose continues to guide us. As we begin this next chapter, we'll keep investing in our people, our partnerships, and the innovation that will help shape the future of Medisca and the pharmaceutical compounding industry."


Working alongside Vice-Chair Maria Zaccardo and Medisca's C-Suite, Dos Santos will continue to guide the company's strategic direction as Medisca continues to expand globally and invest in its long-term growth.


“For over three decades, Medisca has grown by staying true to its purpose while continuing to evolve with the needs of healthcare professionals,” said Maria Zaccardo, Vice-Chair of Medisca. “As we look ahead, we remain focused on supporting our customers, investing in our people, and continuing to strengthen Medisca for the future.”


As part of this leadership transition, Sanjay Goorachurn has stepped down from his role as Chief Executive Officer. Medisca thanks Sanjay for his dedication and contributions to the organization and wishes him continued success.


As Medisca continues to grow globally, the company remains committed to empowering personalized wellness for all by expanding the products, technologies, education, and expertise that help healthcare professionals deliver better patient care around the world.


About Medisca


Founded in 1989, Medisca is a leader in personalized medicine and pharmaceutical supply chain solutions, with a vast portfolio of over 2,000 products completed by a library of 10,000+ proprietary and customized medication formulas, expertise and services in pharmaceutical compounding, continuing healthcare education, and analytical testing. Providing finely-tuned solutions to diverse wellness sectors in numerous markets globally, Medisca is bridging the gaps in healthcare and empowering personalized wellness for all. For more information, visit www.Medisca.com and follow us on LinkedIn, Facebook, and YouTube.


 


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Contacts

Medisca Communications

communications@medisca.com

1-800-665-6334

Capco Recognized by OpenAI for Innovation and Responsible AI Leadership

LONDON - Saturday, 27. June 2026

Receives AI Governance & Risk Excellence Award at OpenAI Partner Summit

Capco’s UK AI Lab wins OpenAI Codex Hackathon

 

(BUSINESS WIRE)--Global management and technology consultancy Capco, a Wipro company, has been recognized by OpenAI for both AI innovation and responsible AI leadership.

Capco received the AI Governance & Risk Excellence Award at the recent OpenAI Partner Summit 2026 in San Francisco, highlighting Capco’s ability to deliver enterprise-grade AI outcomes in highly regulated environments. The award recognizes Capco’s expert advantage when helping financial services and energy organizations to scale AI with confidence, balancing innovation with strong governance to reduce risk, strengthen compliance and improve customer outcomes.

This award follows Capco winning the OpenAI Codex Hackathon, where its UK AI Lab competed against more than 30 teams and over 100 participants from across the OpenAI partner ecosystem. Capco's winning entry Sentra – a consulting-led, AI-powered retail banking solution – uses digital twin technology to identify vulnerable customers and recommend explainable next-best actions for frontline teams.

Srini Pallia, Chief Executive Officer and Managing Director, Wipro Limited, said, “Capco is uniquely positioned to help clients unlock the full value of AI through a consulting-led, AI-powered approach built on deep domain expertise, trust and customer focus. OpenAI’s recognition is a strong validation of the responsible and scalable AI solutions we are building for clients and our own business. These honours mark another important step in accelerating our AI strategy with Wipro Intelligence™ and reinforce Capco’s expert advantage in delivering AI-enabled advisory and scalable solutions that create lasting value.”

Capco was an early OpenAI strategic partner, participating in its beta partner programme since 2025 and working closely with OpenAI on emerging enterprise capabilities. Together, these recognitions reinforce Capco's growing position within the OpenAI partner ecosystem. They demonstrate Capco’s ability to innovate at the frontier of AI technology, while having the requisite expertise to deploy AI responsibly in complex regulatory environments.

About Capco
Capco, a Wipro company, is a global technology and management consultancy shaping change in the financial services and energy industries. For almost 30 years, we have been trusted to help our clients adapt, transform and create long-term value across capital markets, banking, payments, insurance, wealth and asset management, and the energy and utilities sectors. Our deep industry expertise, partnership mindset and award-winning Be Yourself At Work culture are amplified by our strengths in advisory, technology, data and AI innovation. We support our clients to establish clear priorities, connect vision to value, and deliver measurable impact when the stakes are highest. Expert-led, AI-infused, impact-focused – we do not just respond to change, we help shape it. To learn more, visit www.capco.com or follow us on LinkedIn, Instagram, Facebook, and YouTube.

About Wipro Limited
Wipro Limited (NYSE: WIT, BSE: 507685, NSE: WIPRO) is a leading AI-powered technology services and consulting company focused on building innovative solutions that address clients’ most complex digital transformation needs. Leveraging our consulting-led approach and the Wipro Intelligence™ unified suite of AI-powered platforms, solutions and transformative offerings, we help clients realize their boldest ambitions to build intelligent and sustainable businesses. The Wipro Innovation Network – part of the Wipro Intelligence™ suite – underpins our commitment to client-centric co-innovation and co-creation by bringing together capabilities from the innovation labs and partner labs, academia, and global tech communities. With over 240,000 employees and business partners across 65 countries, we deliver on the promise of helping our customers, colleagues, and communities thrive in an ever-changing world. For additional information, visit us at www.wipro.com.

Forward-Looking Statements
The forward-looking statements contained herein represent Wipro’s beliefs regarding future events, many of which are by their nature, inherently uncertain and outside Wipro’s control. Such statements include, but are not limited to, statements regarding Wipro’s growth prospects, its future financial operating results, and its plans, expectations and intentions. Wipro cautions readers that the forward looking statements contained herein are subject to risks and uncertainties that could cause actual results to differ materially from the results anticipated by such statements. Such risks and uncertainties include, but are not limited to, risks and uncertainties regarding fluctuations in our earnings, revenue and profits, our ability to generate and manage growth, complete proposed corporate actions, intense competition in IT services, our ability to maintain our cost advantage, wage increases in India, our ability to attract and retain highly skilled professionals, time and cost overruns on fixed-price, fixed-time frame contracts, client concentration, restrictions on immigration, our ability to manage our international operations, reduced demand for technology in our key focus areas, disruptions in telecommunication networks, our ability to successfully complete and integrate potential acquisitions, liability for damages on our service contracts, the success of the companies in which we make strategic investments, withdrawal of fiscal governmental incentives, political instability, war, legal restrictions on raising capital or acquiring companies outside India, unauthorized use of our intellectual property and general economic conditions affecting our business and industry. Additional risks that could affect our future operating results are more fully described in our filings with the United States Securities and Exchange Commission, including, but not limited to, Annual Reports on Form 20-F. These filings are available at www.sec.gov. We may, from time to time, make additional written and oral forward-looking statements, including statements contained in the company’s filings with the Securities and Exchange Commission and our reports to shareholders. We do not undertake to update any forward-looking statement that may be made from time to time by us or on our behalf.

 

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Contacts
 

Media Contact:
Tim Steele, Head of External Communications
tim.steele@capco.com

Wipro Media Relations – media-relations@wipro.com



Bitget Upgrades CFD Copy Trading With Personalized Risk Controls

 

VICTORIA, Seychelles - Thursday, 25. June 2026

 

(GLOBE NEWSWIRE) -- Bitget, the world’s largest Universal Exchange (UEX), has introduced major upgrades to its CFD Copy Trading system, giving followers greater control over risk management through new position sizing models, independent take-profit and stop-loss settings, and advanced exposure controls.

Copy trading has become one of the most popular ways for users to participate in financial markets, allowing traders to replicate the strategies of experienced market participants. However, as adoption has grown, many users have encountered challenges associated with traditional copy trading models, particularly when differences in risk tolerance and trading style create unintended exposure.

To address these concerns, Bitget’s latest upgrade introduces two new position sizing models. Under Fixed Ratio mode, position sizes are automatically adjusted according to the relative account equity of the follower and the trader being copied, reducing the risks associated with capital mismatches. Fixed Lot mode allows followers to define a predetermined position size for every copied trade, giving users more direct control over their exposure regardless of the trader’s order size.

The update also introduces independent take-profit and stop-loss settings for followers, allowing users to establish personal risk thresholds separate from those of the trader they follow. Once a predefined profit or loss level is reached, positions can be automatically closed based on the follower’s individual settings. Additional controls, including maximum copy lot limits and custom lot multipliers, provide further flexibility for both new and experienced users.

“Copy trading does mean giving up control of your account,” said Gracy Chen, CEO of Bitget. “As users become more sophisticated, they want the ability to benefit from experienced traders while managing risk according to their own objectives. This upgrade shifts copy trading from simple strategy replication toward a more personalized and controlled trading experience.”

The enhancements were developed in response to user feedback and reflect a broader industry shift toward more flexible risk management tools. As traders increasingly participate across crypto and traditional financial markets, demand continues to grow for products that balance accessibility with greater control over capital allocation and risk exposure.

The launch follows Bitget’s continued expansion of its CFD offering within the Universal Exchange ecosystem, which brings together crypto, stocks, commodities, foreign exchange products, and derivatives through a unified trading environment. Earlier this month, Bitget was recognized as the “Best Global Multi-Asset Trading Platform” at the Online Trading Expo, marking the company’s first award in the CFD sector and reflecting growing industry recognition of its multi-asset trading strategy. By strengthening risk management capabilities within copy trading, Bitget continues enhancing the tools and infrastructure available to traders participating across global markets.

For more information, visit here.

About Bitget

Bitget is the world’s largest Universal Exchange (UEX), serving over 125 million users and offering access to over 2M crypto tokens, 100+ tokenized stocks, ETFs, commodities, FX, and precious metals such as gold. The ecosystem is committed to helping users trade smarter with its AI agent, which co-pilots trade execution. Bitget is driving crypto adoption through strategic partnerships with LALIGA and MotoGP™. Aligned with its global impact strategy, Bitget has joined hands with UNICEF to support blockchain education for 1.1 million people by 2027. Bitget currently leads in the tokenized TradFi market, providing the industry’s lowest fees and highest liquidity across 150 regions worldwide.

For more information, visit: Website | Twitter | Telegram | LinkedIn | Discord

Risk Warning: Digital asset prices are subject to fluctuation and may experience significant volatility. Investors are advised to only allocate funds they can afford to lose. The value of any investment may be impacted, and there is a possibility that financial objectives may not be met, nor the principal investment recovered. Independent financial advice should always be sought, and personal financial experience and standing carefully considered. Past performance is not a reliable indicator of future results. Bitget accepts no liability for any potential losses incurred. Nothing contained herein should be construed as financial advice. For further information, please refer to our Terms of Use.

A photo accompanying this announcement is available at:
https://www.globenewswire.com/NewsRoom/AttachmentNg/358c49ac-5ffa-43e6-9ee7-357f2d796ba1

Contacts :

please contact: media@bitget.com

Sultan Bin Ahmed Attends Media Master's Graduation in Spain

 BARCELONA, Spain - Sunday, 28. June 2026



His Highness Sheikh Sultan bin Ahmed bin Sultan Al Qasimi, Deputy Ruler of Sharjah and President of the University of Sharjah (UOS), attended on Friday, at the University of Barcelona, the graduation ceremony of the first cohort of the Master of Science in Media Entrepreneurship and Digital Innovation programme, first of its kind, offered by the University of Sharjah's College of Communication in partnership with the University of Barcelona and with strategic support from Sharjah Media City (Shams).


His Highness expressed his pride in their achievements and praised the strong partnership between the two universities, which share a commitment to knowledge, excellence and global understanding. His Highness stressed that graduation marks the beginning of a new journey rather than its conclusion.


His Highness likened the graduates to ships leaving a safe harbour, noting that ships are built to sail beyond the horizon, to embrace the unknown, and to discover new worlds. He said the graduates are embarking on a future filled with opportunities, challenges and achievements, equipped with the knowledge, resilience and determination to succeed.


His Highness added that this vision reflects the UAE's values, whose forefathers believed prosperity comes from engaging with the wider world, learning from it and contributing to it. His Highness described the master's programme as a modern expression of this belief, connecting Sharjah and Barcelona while bringing together two distinguished institutions, cultures and traditions of excellence. The programme enables students to benefit from the intellectual and cultural strengths of both countries, preparing them for successful careers in an increasingly interconnected world.


His Highness stressed that the specialization is a special hub where bright new ideas are born, information is examined, interpreted and shaped before sharing it with the world. The digitalized era has altered information speed and dissemination, allowing the stories, platforms and narratives that they create to reach audiences across the globe, a power that needs humility, integrity and insight.


His Highness highlighted Shams’s role as the third strategic partner, building a solid collaboration between academia, industry and the creative economy. His Highness said this partnership equips graduates with practical experience, exposure to diverse perspectives and the skills needed to address real-world challenges. His Highness encouraged graduates to continue seeking knowledge and inspiring others, while expressing appreciation to their families and the academic and administrative staff of both universities.


His Highness presented graduation certificates to 24 graduates, congratulated them, and wished them success in their future careers.


Before the ceremony, His Highness met with Dr Joan Guàrdia Olmos, the Rector of the University of Barcelona, to discuss ways to strengthen academic and scientific cooperation. His Highness also toured the university's academic facilities, graduation hall, library and collection of rare manuscripts and books.


On the sidelines of the visit, His Highness attended the signing of a memorandum of understanding between Sharjah Media City (Shams) and the Faculty of Philology and Communication at the University of Barcelona. The agreement was signed by Rashid Abdullah Al Obad, Director General of Sharjah Media City (Shams), and Dr Joan G. Burguera, Dean of the Faculty of Philology and Communication at the University of Barcelona. It establishes a framework for cooperation in media, digital innovation, entrepreneurship, scientific research and the creative industries.


The memorandum also promotes academic and professional exchanges, training programmes, conferences, seminars, and workshops, while supporting national talent, fostering entrepreneurship, and helping transform innovative student projects into marketable media products, reinforcing Shams' commitment to partnerships with leading academic institutions.



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Contacts

Hussain Al Mulla


Hussain.AlMulla@SGMB.ae

Venture Global Announces Closing of $1.5 Billion Senior Secured Vessel Financing Facility

 


ARLINGTON, Va. - 

(BUSINESS WIRE)--Venture Global, Inc. (NYSE: VG) announced today that its wholly-owned subsidiary, Venture Global Shipping Holdings, LLC (“VGSH”), has entered into a Credit and Guaranty Agreement providing for a senior secured term loan facility (the “Facility”) in an aggregate principal amount of up to $1,500,000,000. The Facility will mature on June 26, 2032.


Deutsche Bank and ING acted as coordinating lead arrangers for the Facility. ING also serves as facility agent and security trustee.


VGSH intends to use the net proceeds from the Facility for general corporate purposes, including to reimburse Venture Global LNG, Inc. for payments previously made by it or its affiliates in connection with the acquisition of nine LNG carriers, funding certain reserve accounts, and paying transaction fees and expenses.


About Venture Global


Venture Global is an American producer and exporter of low-cost U.S. liquefied natural gas (“LNG”) with over 100 MTPA of capacity in production, construction, or development. Venture Global began producing LNG from its first facility in 2022 and is now one of the largest LNG exporters in the United States. The company’s vertically integrated business includes assets across the LNG supply chain including LNG production, natural gas transport, shipping and regasification. Venture Global’s first three projects, Calcasieu Pass, Plaquemines LNG, and CP2 LNG, are located in Louisiana along the Gulf of America. Venture Global is developing Carbon Capture and Sequestration projects at each of its LNG facilities.


Forward-Looking Statements


This press release contains certain statements that may include “forward-looking statements.” All statements, other than statements of historical or present facts or conditions, included herein are “forward-looking statements.” Included among “forward-looking statements” are, among other things, statements regarding Venture Global’s business strategy, plans and objectives, including the use of proceeds from the financing. Venture Global believes that the expectations reflected in these “forward-looking statements” are reasonable, they are inherently uncertain and involve a number of risks and uncertainties beyond Venture Global’s control. In addition, assumptions may prove to be inaccurate. Actual results may differ materially from those anticipated or implied in “forward-looking statements” as a result of a variety of factors. These “forward-looking statements” speak only as of the date made, and other than as required by law, Venture Global undertakes no obligation to update or revise any “forward-looking statement” or provide reasons why actual results may differ, whether as a result of new information, future events or otherwise.


 


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Contacts

 

Investor Contact

Ben Nolan

IR@ventureglobalLNG.com


Media Contact

Shaylyn Hynes

press@ventureglobalLNG.com


 

Sunday, June 28, 2026

VerSprite Launches Fork and Knife: AI-Driven Threat Modeling and Adversarial Testing Built for the Speed of Modern Software


 ATLANTA -

Powered by the risk-centric PASTA methodology and two decades of accredited offensive security, the integrated platform lets enterprises threat model in a security sprint—then prove the risk through AI-led, human-on-the-loop testing.


(BUSINESS WIRE)--VerSprite, a global leader in risk-based threat modeling and the firm behind the PASTA (Process for Attack Simulation and Threat Analysis) methodology, today announced the general availability of Fork (www.forktm.com), a continuous application threat modeling platform, alongside Knife, an AI-led, human-on-the-loop adversarial testing platform for web applications and web API endpoints. Together, the two products operationalize a new model for product security—one where applications are securely designed, continuously modeled, and actively tested as part of the build process itself.


The launch addresses a problem every security leader knows but few tools have solved: threat modeling is essential, never more so than in an AI-driven era, yet it has remained slow, manual, and anchored to frameworks designed for a different threat landscape.


The problem: threat modeling matters more than ever—and most tools are stuck in 2005


For two decades, application threat modeling has leaned heavily on STRIDE—a categorization mnemonic for spoofing, tampering, repudiation, information disclosure, denial of service, and elevation of privilege. STRIDE is useful for sorting threats into buckets, but it was never a methodology. It does not ingest real-time threat intelligence, it does not weigh business impact, and its static categories say nothing about the adversary behaviors defining risk today—persistence, extortion, double-extortion ransomware, supply-chain compromise, and the novel attack surfaces introduced by AI-enabled applications.


The result is a familiar bottleneck. Threat modeling gets treated as a one-time, document-heavy exercise that lands too late in the lifecycle, goes stale the moment an application changes, and rarely connects to the testing that would actually validate whether a threat is real. As organizations ship faster and adopt AI across the stack, the gap between how quickly software evolves and how slowly it gets modeled has become a material risk.


The solution: risk-centric threat modeling at sprint speed


Fork is a practical, software-driven implementation of PASTA—the only risk-centric, business-aligned threat modeling methodology, co-authored by VerSprite founder and CEO Tony UcedaVelez. Rather than categorizing threats in the abstract, PASTA’s seven stages move from business objectives through attack surface, application decomposition, threat analysis, weakness and vulnerability analysis, attack modeling, and finally risk and impact analysis—so the threats that surface are the ones most likely to happen and most damaging if they do.


Fork brings that rigor to the cadence of modern development, enabling teams to produce a defensible, risk-prioritized threat model in under two hours and keep it current from Sprint 1 onward. Key capabilities include:


AI-accelerated attack trees. Fork’s AI capabilities intelligently trim the attack tree for an application, removing noise and focusing analysts on viable, high-impact paths instead of exhaustive theoretical ones.

Contextualized, threat-informed models. Fork enriches every model with live cyber threat intelligence, the latest vulnerability data across a product’s full technology stack, and viable attack vectors substantiated through real adversarial testing.

Industry-aligned taxonomies. The platform automatically correlates findings with trusted MITRE and OWASP frameworks—including CWE, CVE with EPSS scoring, CAPEC, ATT&CK, D3FEND, and ASVS—to drive targeted, defensible mitigations.

A proprietary residual risk formula. As tests complete and conditions change, Fork recalculates residual risk so leaders always have an accurate, current view of exposure.

A single pane of glass. Industry threats, an application’s attack surface, and threat intelligence converge into one unified, collaborative view for security, engineering, product, and business stakeholders.

From blueprint to proof: introducing Knife


A threat model defines which attack paths matter most. Knife proves them.


VerSprite is debuting Knife, an AI-led, human-on-the-loop adversarial platform for web applications and web API endpoints, trained on more than 20 years of accredited, industry-recognized offensive security work from VerSprite’s BREAKERS OffSec team. Where Fork serves as the blueprint for adversarial testing, Knife executes against that blueprint—pairing the scale and speed of AI with expert human oversight to validate exploitability with real-world fidelity.


The integration closes the loop that has long separated threat modeling from testing. From within a Fork threat model, teams can request targeted, on-demand testing of specific weaknesses and attack patterns. Knife runs the assessment; results flow back into the model; and Fork updates the residual risk of the product automatically. Threat modeling and adversarial testing stop being sequential, disconnected events and become a continuous, self-updating system.


A new operating model: AI SecOps


“The future of product and software security is an integrated model of AI SecOps—where products are securely designed and tested as part of the functional build process, not bolted on afterward. STRIDE gave the industry a vocabulary. PASTA gave it a methodology. Fork and Knife now give it operational speed—continuous threat modeling and integrated, AI-led testing that keeps pace with how software is actually built and how adversaries actually behave.”


— Tony UcedaVelez, CEO and founder of VerSprite and co-author of the PASTA methodology


Operationalized visibility through deep integrations


Fork is designed to supercharge, not replace, the security tooling enterprises already run. Through integrations across the AppSec ecosystem—spanning SAST, DAST, and software composition analysis, vulnerability scanning, cloud security posture, attack surface management (CASM), penetration testing platforms, and IT service management—Fork turns scattered findings into a living risk picture. Connected and roadmapped integrations include ServiceNow, Veracode, Snyk, Semgrep, Checkmarx, OpenCTI, Qualys, Tenable, Mandiant, and Archer, among others.


The payoff is real-time visibility, operationalized: as continuous and on-demand tests complete and report back, a product’s threat model and residual risk update at the speed of delivery—giving security and product leaders an always-current understanding of what could go wrong, how likely it is, and what it would cost the business.


Availability


Fork is available today. A free Fork Community edition supports a single application threat model with vulnerability ingestion via SBOM or OVAL, while Fork Enterprise unlocks unlimited applications and teams, all integrations, SSO, granular access controls, and audit logging. Fork Enterprise PT extends the platform with on-demand adversarial testing—powered by Knife and VerSprite’s BREAKERS team—requested directly from within a threat model. VerSprite also offers Threat Modeling as a Service for organizations seeking expert-led training and managed delivery.


To learn more, request a demo, or start for free, visit www.forktm.com.


About VerSprite


VerSprite is a global cybersecurity firm specializing in risk-based threat modeling, offensive security, and managed security services. Founded in 2007 and headquartered in Atlanta, Georgia, VerSprite is the originator of the PASTA (Process for Attack Simulation and Threat Analysis) methodology and partners with Fortune 500 enterprises and product organizations worldwide to reduce cyber risk through a structured, data-driven, adversary-informed approach. Learn more at www.versprite.com.


About Fork


Fork is VerSprite’s continuous application threat modeling platform. Built on the PASTA methodology and accelerated by AI, Fork enables security, engineering, and product teams to produce risk-centric threat models in under two hours, contextualize them with live threat intelligence and full-stack vulnerability data, and keep them continuously aligned with how applications evolve—now with integrated, AI-led adversarial testing through Knife.


 


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Contacts

 

Tim Deleon

beetle@versprite.com

7079278611


www.versprite.com

Saturday, June 27, 2026

DAYBU® (trofinetide) Recommended for Approval in the European Union by CHMP

 -- European Commission decision expected in the coming months


-- If approved, DAYBU® would become the first treatment for neurobehavioral symptoms of Rett syndrome in the European Union


(BUSINESS WIRE) -- Acadia Pharmaceuticals Inc. (Nasdaq: ACAD) today announced that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has adopted a positive opinion following a re-examination procedure, recommending the granting of a marketing authorization for DAYBU® (trofinetide) for the treatment of neurobehavioral symptoms of Rett syndrome in adults and pediatric patients aged five years and older. If granted marketing authorization by the European Commission, DAYBU® would be the first therapy approved for this indication in the European Union (EU).


“The CHMP’s positive opinion for DAYBU® is an important milestone in our mission to bring this innovative therapy to the EU, where there are no therapies specifically approved for the neurobehavioral symptoms of this devastating condition," said Catherine Owen Adams, Acadia’s Chief Executive Officer. “Our commitment is to make a meaningful difference in the lives of patients, caregivers, and the wider Rett community by addressing this significant unmet need, and we are very pleased with the outcome of the re-examination process."


The CHMP’s recommendation is primarily based on results from the Phase 3 LAVENDER™ study, which demonstrated statistically significant and clinically meaningful improvements in core features of Rett syndrome, as measured by the Rett Syndrome Behaviour Questionnaire (RSBQ) and Clinical Global Impression-Improvement (CGI-I) scale. Importantly, these findings indicate that treatment with DAYBU® can address some of the most impactful aspects of Rett syndrome, which severely impact quality of life for patients and caregivers.


"For decades, families in Europe affected by Rett syndrome have had no medicine specifically approved for the neurobehavioral symptoms of this condition, despite the profound impact they have on almost every aspect of daily life,” said Pedro Rocha, President of Rett Syndrome Europe. “The CHMP’s positive opinion represents hope for thousands of European Union individuals living with this devastating condition, their families and caregivers."


Following the CHMP recommendation, the European Commission will review the opinion and is expected to issue a final decision in the coming months. If DAYBU® is approved, the marketing authorization would apply to all 27 EU member states, as well as Iceland, Liechtenstein, and Norway.


About Rett Syndrome

Rett syndrome is a rare, complex, neurodevelopmental disorder and occurs in approximately one of every 10,000 to 15,000 female births worldwide.1-3 A child with Rett syndrome generally exhibits an early period of apparently normal development until six to 18 months, when many of their skills seem to slow down or stagnate. This is typically followed by a regression phase when the child loses acquired communication skills and purposeful hand use. The child may then experience a plateau period in which they could show mild recovery in cognitive interests, but body movements remain severely diminished. As they age, those individuals living with Rett may continue to experience a stage of motor deterioration, which can last the rest of the patient’s life.2 Rett syndrome is typically caused by a genetic mutation on the MECP2 gene.4 In preclinical studies, deficiency in MeCP2 function is thought to lead to impairment in synaptic communication and brain plasticity, and the deficits in synaptic function may be associated with Rett manifestations.4-6


Symptoms of Rett syndrome may also include development of hand stereotypies, such as hand wringing and clapping, and gait abnormalities.7 Most individuals living with Rett syndrome typically live into adulthood and require intense round-the-clock care.1,8


About DAYBU®

DAYBU® (trofinetide) is a synthetic analog of the N-terminal tripeptide of insulin-like growth factor 1.


About Acadia Pharmaceuticals

Acadia is committed to turning scientific promise into meaningful innovation that makes the difference for underserved neurological and rare disease communities around the world. Our commercial portfolio includes the first and only FDA-approved treatments for Parkinson’s disease psychosis and Rett syndrome. We are developing the next wave of therapeutic advancements with a robust and diverse pipeline that includes mid- to late-stage programs in Alzheimer’s disease psychosis and Lewy body dementia psychosis, along with earlier-stage programs that address other underserved patient needs. At Acadia, we’re here to be their difference. For more information, visit us at acadia.com and follow us on LinkedIn and X.


Forward-Looking Statements


This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Forward-looking statements include all statements other than statements of historical fact and can be identified by terms such as “may,” “will,” “should,” “could,” “would,” “intends,” “expects,” “plans,” “anticipates,” “believes,” “estimates,” “projects,” “predicts,” “potential,” “guidance,” “continue” and similar expressions (including the negative thereof) intended to identify forward-looking statements. Forward-looking statements contained in this press release include, but are not limited to, statements about the expected or potential approval of trofinetide or DAYBU® by the European Commission, including the potential timing of such approval, and if approved, the potential benefits of trofinetide as a treatment of the neurobehavioral symptoms of Rett Syndrome and the importance of trofinetide to patients, caregivers and the Rett community. Forward-looking statements are subject to known and unknown risks, uncertainties, assumptions and other factors that may cause our actual results, performance or achievements to differ materially and adversely from those anticipated or implied by our forward-looking statements. Such risks, uncertainties and other factors include, but are not limited to, the inherent uncertainty regarding development of product candidates, including approval of trofinetide by the European Commission; our dependency on the continued successful commercialization of our products and our ability to maintain or increase sales of our products; our ability to obtain necessary regulatory approvals to commercialize our products and product candidates; if and when approved, market acceptance of our products and our ability to continue to stay in compliance with applicable laws and regulations. Given the risks and uncertainties, you should not place undue reliance on these forward-looking statements. For a discussion of these and other risks, uncertainties and other factors that may cause our actual results, performance or achievements to differ, please refer to our quarterly report on Form 10-Q for the period ended March 31, 2026, filed on May 7, 2026, as well as our subsequent filings with the Securities and Exchange Commission from time to time. The forward-looking statements contained herein are made as of the date hereof, and we undertake no obligation to update them after this date, except as required by law.


References

1 Fu C, Armstrong D, Marsh E, et al. Consensus guidelines on managing Rett syndrome across the lifespan. BMJ Paediatrics Open. 2020;4:e000717.

2 Kyle SM, Vashi N, Justice MJ. Rett syndrome: a neurological disorder with metabolic components. Open Biol. 2018; 8:170216.

3 May DM, Neul JL, Satija A, et al. Real-world clinical management of individuals with Rett syndrome: a physician survey. J Med Econ. 2023;26(1):1570-1580.

4 Amir RE, Van den Veyver IB, Wan M, et al. Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2. Nat Genet. 1999; 23(2):185-188.

5 Fukuda T, Itoh M, Ichikawa T, et al. Delayed maturation of neuronal architecture and synaptogenesis in cerebral cortex of Mecp2-deficient mice. J Neuropathol Exp Neurol. 2005; 64(6):537-544.

6 Asaka Y, Jugloff DG, Zhang L, et al. Hippocampal synaptic plasticity is impaired in the Mecp2-null mouse model of Rett syndrome. Neurobiol Dis. 2006; 21(1):217-227.

7 Neul JL, Kaufmann WE, Glaze DG, et al. Rett syndrome: revised diagnostic criteria and nomenclature. Ann Neurol. 2010; 68(6):944-950.

8 Tarquinio DO, Hou W, Neul JL, et al. The changing face of survival in Rett syndrome and MECP2-related disorders. Pediatr Neurol. 2015; 53(5):402-411.


 


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https://www.aetoswire.com/en/news/2606202655913


Contacts

Investor Contact:

Acadia Pharmaceuticals Inc.

Al Kildani

(858) 261-2872

ir@acadia-pharm.com


Acadia Pharmaceuticals Inc.

Jessica Tieszen

(858) 261-2950

ir@acadia-pharm.com


Media Contact:

Acadia Pharmaceuticals Inc.

Deb Kazenelson

(818) 395-3043

media@acadia-pharm.com


 

Friday, June 26, 2026

Fossil Fuels Are a Thing of the Past; The Future Is Renewable: The Smarter E Europe Concludes With a Clear Message

 MUNICH & PFORZHEIM, Germany - Friday, 26. June 2026 AETOSWire 


 



(BUSINESS WIRE)--Packed halls, a vibrant atmosphere and a buzzing vibe – after three days, The smarter E Europe 2026, Europe’s largest alliance of exhibitions for the energy industry, has come to a successful close. The event held at Messe München offered a glimpse of a future-oriented energy world powered by renewables. A strong signal with a clear message went out to the world from the Bavarian capital: The future is renewable. Renewable energies can help ensure a reliable, secure and cost-effective energy supply around the clock, seven days a week. A total of 2,650 exhibitors from 52 countries – many of whom had expanded their booth space compared with the previous year – demonstrated how this can work. More than 66 percent of exhibitors were from outside of Germany. They presented innovative and market-ready products ranging from virtual power plants, smart grid and load control, smart charging solutions, storage technologies and PV hybrid systems to digital platforms transparently and flexibly. The technical program began on June 22 and 23, 2026, with four specialist conferences as part of The smarter E Europe. Including the side events, more than 3,000 participants gathered for an intensive exchange of knowledge and discussions on the latest industry developments. At the exhibition grounds, approximately 105,000 trade visitors from 163 countries took the opportunity to learn about new trends across industries and sectors, to network and to gain insight into the energy system of tomorrow.


Across all 19 exhibition halls and the Outdoor Area, there was a palpable sense of enthusiasm for contributing to major societal change and advancing the energy transition. “We are in the midst of a global transformation toward a completely new energy system. We cannot stop this revolution and must seize all the opportunities that exhibitors have shown us," says energy expert and author Dr. Tim Meyer.


Affordable and grid-friendly


He also led a tour of the special exhibit Renewables 24/7 – Secure Energy for a Changing World, which was among the exhibition’s highlights. “Fossil fuels are a thing of the past; the future clearly belongs to renewables. Over the three days of the exhibition, we demonstrated through practical examples and scientific evidence that renewables provide reliability, resilience and efficiency while making economic sense. That is why the path toward a renewable future must be pursued consistently. There can be no turning back,” explains Markus Elsässer, founder and CEO of Solar Promotion GmbH. “This year, with our focus on Renewables 24/7, we addressed the right topic at the right time. We have shown that we are thinking ahead and helping shape the future,” says Jens Mohrmann, Managing Director of Freiburg Wirtschaft Touristik und Messe GmbH & Co. KG (FWTM).


The smarter E Europe is organized by Solar Promotion GmbH and Freiburg Wirtschaft Touristik und Messe GmbH & Co. KG (FWTM).


 


View source version on businesswire.com: https://www.businesswire.com/news/home/20260625641253/en/



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https://www.aetoswire.com/en/news/54560344


Contacts

 

Solar Promotion GmbH | P.O. Box 100 170 | 75101 Pforzheim

Horst Dufner | Tel.: +49 7231 58598-0 | Fax: +49 7231 58598-28

dufner@solarpromotion.de


Press contact:

Solar Promotion GmbH | P.O. Box 100 170 | 75101 Pforzheim

Peggy Härter-Zilay | Tel.: +49 7231 58598-240

haerter-zilay@solarpromotion.com


 

Bitget Rewards Cross-Market Trading With New VIP Miracle Badge Program

 

VICTORIA, Seychelles - Wednesday, 24. June 2026

(GLOBE NEWSWIRE) -- Bitget, the world's largest Universal Exchange (UEX), has launched the VIP Miracle Badge Program, a new initiative designed to recognize active traders across crypto, stocks, and CFD markets while expanding access to premium services and exclusive rewards. The program introduces a series of achievement badges tied to trading activity across multiple asset classes and forms part of Bitget's broader effort to build a comprehensive VIP ecosystem for multi-asset traders.

As trading increasingly moves beyond a single asset class, users are building strategies across crypto, equities, commodities, foreign exchange products, and derivatives. The VIP Miracle Badge Program was created to recognize that evolution, rewarding traders who actively participate across the broader Universal Exchange ecosystem rather than within a single market segment.

“Most traders today rarely stay within one market,” said Gracy Chen, CEO of Bitget. “As users diversify their portfolios and move across markets, expectations around service, execution, and access continue to evolve. The VIP Miracle Badge Program builds on our VIP offering by recognizing trading achievements while giving users access to services and experiences designed for a multi-asset environment.”

The VIP Miracle Badge Program introduces four achievement categories based on trading participation and performance across different markets. The UEX Trading Master badge recognizes users active across multiple asset classes. The Futures Trading Master badge is designed for derivatives traders, while the Stock Trading Master and CFD Trading Master badges recognize participation across tokenized equities, commodities, foreign exchange products, and global indices.

The launch follows a series of initiatives aimed at expanding access to Bitget's VIP services. Recent programs include the VIP Fast Track Program, which allows eligible traders to access VIP benefits more efficiently, and the VIP Airdrop Season, which provides exclusive opportunities across products and asset categories. Together, these initiatives support Bitget's Universal Exchange strategy by creating a more connected experience for users participating across crypto and traditional financial markets.

As Bitget continues to expand access to tokenized stocks, commodities, foreign exchange products, and digital assets through a single platform, the VIP Miracle Badge Program adds a new layer of recognition and rewards for traders operating across global markets. The initiative reflects the growing role of multi-asset participation within the Universal Exchange ecosystem and the increasing demand for services built around the needs of active traders.

For more information, visit: https://www.bitget.com/activity/vip-medal

About Bitget

Bitget is the world's largest Universal Exchange (UEX), serving over 125 million users and offering access to over 2M crypto tokens, 500+ tokenized stocks, ETFs, commodities, FX, and precious metals such as gold. The ecosystem is committed to helping users trade smarter with its AI agent, which co-pilots trade execution. Bitget is driving crypto adoption through strategic partnerships with LALIGA and MotoGP™. Aligned with its global impact strategy, Bitget has joined hands with UNICEF to support blockchain education for 1.1 million people by 2027. Bitget currently leads in the tokenized TradFi market, providing the industry's lowest fees and highest liquidity across 150 regions worldwide.

For more information, visit: Website | Twitter | Telegram | LinkedIn | Discord

Risk Warning: Digital asset prices are subject to fluctuation and may experience significant volatility. Investors are advised to only allocate funds they can afford to lose. The value of any investment may be impacted, and there is a possibility that financial objectives may not be met, nor the principal investment recovered. Independent financial advice should always be sought, and personal financial experience and standing carefully considered. Past performance is not a reliable indicator of future results. Bitget accepts no liability for any potential losses incurred. Nothing contained herein should be construed as financial advice. For further information, please refer to our Terms of Use.

A photo accompanying this announcement is available at https://www.globenewswire.com/NewsRoom/AttachmentNg/8d9ffa59-32f5-4166-b351-f243ec0be350

Contacts :

For media inquiries, please contact: media@bitget.com