Amazon Customers Shop at Record Levels Again This Holiday Season – Cyber Monday 2019 Becomes the Single Biggest Shopping Day in the Company’s History

Amazon Customers Worldwide Order Hundreds of Millions of Items Between Thanksgiving and Cyber Monday

Record-breaking Black Friday for Amazon this year – the best-ever Black Friday in the company’s history

More Items Purchased from Independent Third-Party Sellers— Mostly Small and Medium-Sized Businesses – on Cyber Monday 2019 than Ever Before on a Single Day

Customers Purchased a Record-Breaking Number of Amazon Devices – The Best-Selling Products in Amazon’s Stores Globally were Echo Dot and Fire TV Stick 4K with Alexa Voice Remote


SEATTLE-Wednesday 4 December 2019 [ AETOS Wire ]

(BUSINESS WIRE) -- (NASDAQ:AMZN) – Amazon today announced that Cyber Monday was once again the single biggest shopping day in the company’s history, based on the number of items ordered worldwide. Customers all around the world shopped at record levels across a wide selection, with hundreds of millions of products ordered worldwide between Thanksgiving and Cyber Monday, alone. Customers purchased millions more Amazon Devices compared to the same period last year in Amazon’s Stores globally and the best-selling items were Echo Dot and Fire TV Stick 4K with Alexa Voice Remote.

“We’re focused on making this holiday season more convenient than ever for our customers, especially given how short this holiday shopping season will be,” said Jeff Wilke, CEO Worldwide Consumer, Amazon. “We are thrilled that customers continue to come to Amazon in record numbers to discover what they need and want for the holidays. Thank you to our customers and employees all around the world for making this holiday shopping weekend the best yet.”

Holiday Weekend Highlights:

    Customers worldwide purchased more toys this Black Friday and Cyber Monday combined than ever before. Among the tens of millions of toys purchased during this time period, best-sellers included LEGO Star Wars Darth Vader's Castle, Monopoly Game: Disney Frozen 2 Edition and Hasbro games such as Jenga, Guess Who and Candy Land Kingdom of Sweet Adventures.
    Cyber Monday was the single biggest shopping day for Amazon Fashion worldwide, with more items purchased than any other single day in the company’s history. Best-sellers included Carhartt Men’s Acrylic Watch Hat and Champion Men’s Powerblend Fleece Pullover Hoodie.
    Amazon customers worldwide ordered more than 25 million home items on Black Friday and Cyber Monday, combined.
    Best-sellers on Black Friday in the U.S. included Echo Dot, Fire TV Stick with Alexa Voice Remote, Instant Pot Duo80 – 8 Quart, 23andMe Health + Ancestry Service: Personal Genetic DNA Test, L.O.L. Surprise! Winter Disco Bigger Surprise and iRobot Roomba 675 Robot Vacuum.
    Customers worldwide purchased more than four million beauty products this Cyber Monday compared to last year, with best-sellers including Oral-B Genius Pro 900 Electric Toothbrush, Lagunamoon Essential Oils Top 6 Gift Set and L'Oreal Paris Voluminous Makeup Lash Paradise Mascara.
    Top-selling categories worldwide include Toys, Home, Fashion and Health and Personal Care.
    The best-selling products in Amazon’s Stores on Cyber Monday in the U.S. included Echo Dot, Fire TV Stick with Alexa Voice Remote, Play-Doh Sweet Shoppe Cookie Creations, Keurig K-Cafe Coffee Maker and LEGO City Ambulance Helicopter 60179 Building Kit.
    Independent third-party sellers in Amazon’s Stores — mostly small and medium-sized businesses – sold more items during Cyber Monday 2019 than any other 24-hour period in the company’s history.
    For the third year in a row, Whole Foods Market broke its all-time record of turkeys sold during the Thanksgiving season.
    Amazon delivered millions of grocery items to Prime members in the U.S. through the five days between Thanksgiving and Cyber Monday. Best sellers from Amazon Fresh and Whole Foods Market delivery included Honeycrisp apples, lemons and avocados.
    Top selling items at Amazon Books and Amazon 4-star stores over the holiday weekend included the Amazon Smart Plug, Echo Dot and All-New Echo Dot Smart Speaker with Clock, L.O.L. Surprise! Dolls, Wrecking Ball (Diary of a Wimpy Kid Book 14), and the Wyze Cam 1080p HD Indoor Wireless Smart Home Camera with Night Vision.

Record-Breaking Weekend for Devices

    Shoppers purchased a record number of Amazon Devices globally this holiday weekend.
    Amazon customers worldwide purchased millions more Amazon Devices, compared to the same period last year in Amazon’s Stores globally, including Echo devices, Fire TV devices, Kindle devices, and Fire tablets.
    It was a record-breaking holiday shopping weekend for smart home devices in Amazon’s Stores globally with shoppers purchasing millions of smart home devices, including iRobot Roomba 675 Robot Vacuum, Furbo Dog Camera, and Wemo Mini Smart Plug.
    The best-selling products in Amazon’s Stores globally were Echo Dot and Fire TV Stick 4K with Alexa Voice Remote.

Holidays Made Fast, Free and Convenient

    Ultrafast and FREE grocery delivery: Now Prime members get free and fast grocery delivery from Amazon Fresh and Whole Foods Market. Selection includes a variety of products for all your holiday needs from meat to seafood, produce, snacks, and household essentials, with options for fast one- and two-hour delivery windows. Prime members who live in one of the more than 2,000 cities and towns where grocery delivery is available can request an invitation to shop Amazon Fresh or Whole Foods Market delivery. Learn more at amazon.com/grocery.
    Procrastinators Delight: In addition to free delivery on more than 100 million items for all Amazon customers, Prime members in the U.S. can shop a selection of over 10 million items for Prime Free One-Day Delivery and millions of items available for Same-Day Delivery in 46 major metropolitan areas.
    More Delivery Options Than Ever: This holiday season, customers can pick-up their packages at a number of Amazon Hub locations including thousands of in-store staffed Counter pickup points across the U.S. within Rite Aid, GNC and Stage stores, as well as at Health Mart independent pharmacies. Additionally, tens of millions of products can be easily and conveniently delivered to 900 cities and towns across the country via Locker or Locker+. To find an Amazon Hub location, visit amazon.com/Hub. In addition, Prime members in 50 U.S. cities and surrounding areas can also enjoy secure, convenient package delivery with Key by Amazon (amazon.com/key). Prime members who don’t want to spoil the surprise by having their package arrive on a day when their loved ones are home can use Amazon Day (amazon.com/amazonday) to select a personalized delivery day for their holiday purchases.

SOCIAL HANDLES:

Facebook: @Amazon
Instagram: @Amazon
Twitter: @Amazon
Landing Page: amazon.com/cybermonday

About Amazon

Amazon is guided by four principles: customer obsession rather than competitor focus, passion for invention, commitment to operational excellence, and long-term thinking. Customer reviews, 1-Click shopping, personalized recommendations, Prime, Fulfillment by Amazon, AWS, Kindle Direct Publishing, Kindle, Fire tablets, Fire TV, Amazon Echo, and Alexa are some of the products and services pioneered by Amazon. For more information, visit amazon.com/about and follow @AmazonNews.

View source version on businesswire.com: https://www.businesswire.com/news/home/20191203005397/en/

Contacts

Amazon.com, Inc.
Media Hotline
Amazon-pr@amazon.com
www.amazon.com/pr

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P&G 2019 Citizenship Report Highlights Commitment to Community Impact, Gender Equality, Diversity & Inclusion and Sustainability

Company’s Focus on Being a Force for Good and Force for Growth is Underpinned by Higher Reputation Rankings CINCINNATI-Wednesday 4 December 2019 [ AETOS Wire ]

(BUSINESS WIRE) -- The Procter & Gamble Company (NYSE:PG) today released its 2019 Citizenship Report, detailing progress in its Citizenship focus areas of Community Impact, Diversity & Inclusion, Gender Equality and Environmental Sustainability built on the foundation of Ethics and Corporate Responsibility.

From reaching its 2020 goal of providing 15 billion liters of clean water through its Children’s Safe Drinking Water (CSDW) Program, to using its voice to spark conversations about gender and racial equality, 2019 was a year in which P&G’s leadership made a meaningful impact in the community and with the Company’s employees.

“We’ve built Citizenship into our business, and it’s not only doing good, it’s building trust and equity with consumers, and driving growth and value creation—allowing us to be a force for good and a force for growth,” said David Taylor, P&G’s Chairman of the Board, President and Chief Executive Officer. “It’s not a separate thing we do on the side—it’s how we do business every day around the world.”

With operations in about 70 countries serving nearly five billion people, the Company leverages its scale, innovation and talented employees, along with the reach of its 65 leadership brands, to do good every day. P&G’s contributions have been recognized externally with higher 2019 rankings on Fortune’s World’s Most Admired Companies and the Axios Harris Poll 100.

In addition, more than 80% of P&G’s employees expressed a favorable opinion about the Company’s Citizenship efforts, making Citizenship a high-scoring index in the Company’s 2019 annual survey.

Highlights of the P&G 2019 Citizenship Report include:

    Community Impact: P&G provided disaster relief kits filled with its products to families affected by more than 25 natural disasters including wildfires and hurricanes that devastated parts of the U.S., flooding in the Indian state of Kerala, and the deadly earthquake and tsunami that hit Indonesia. Additionally, the Company, through its CSDW Program, made a new commitment to delivering 25 billion liters of clean drinking water by 2025.

    Diversity & Inclusion: P&G was a platinum sponsor of World Pride in New York with 50 sites around the world showing support through various Pride activities. The Company launched “The Look,” the sequel to the Emmy Award-winning film “The Talk,” to continue the conversation about racial bias. P&G also established neurodiversity programs at four Company sites to provide opportunities for individuals on the autism spectrum.

    Gender Equality: Well on the way to P&G’s goal of 50/50 representation at all levels, the Company’s senior leadership team and Board of Directors are now composed of more than 40 percent women. P&G’s Always brand launched its #EndPeriodPoverty Campaign to help keep girls in school, and Secret donated more than $500,000 as part of the brand’s ongoing support for the U.S. Women’s National Soccer Team’s fight for equal pay.

    Environmental Responsibility: In April, the Company marked its one-year anniversary of Ambition 2030 – a set of bold sustainability goals encompassing P&G’s brands, supply chain, society and employees. P&G also partnered with TerraCycle to introduce the “milkman” concept of reusable packaging with Loop. Along with many steps the Company is taking to help solve the global issue of plastic waste, it joined forces with more than 40 companies to form the Alliance to End Plastic Waste and committed to reduce global use of virgin petroleum plastic in product packaging by 50% by 2030.

This is the 20th consecutive year P&G has issued a report on the Company’s efforts to have a positive impact on the world, beginning with P&G’s first Sustainability Report in 1999. The Executive Summary, a 24-page overview of the progress and stories, is available online as well as a 140+ page detailed version of the report.

About Procter & Gamble

P&G serves consumers around the world with one of the strongest portfolios of trusted, quality, leadership brands, including Always®, Ambi Pur®, Ariel®, Bounty®, Charmin®, Crest®, Dawn®, Downy®, Fairy®, Febreze®, Gain®, Gillette®, Head & Shoulders®, Lenor®, Olay®, Oral-B®, Pampers®, Pantene®, SK-II®, Tide®, Vicks®, and Whisper®. The P&G community includes operations in approximately 70 countries worldwide. Please visit http://www.pg.com for the latest news and information about P&G and its brands.

This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20191202005577/en/

Contacts

Julie deSylva, Global Company Communications
513-780-0006
Desylva.j@pg.com

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Andersen Global Expands Presence in Mozambique

SAN FRANCISCO-Wednesday 4 December 2019 [ AETOS Wire ]

(BUSINESS WIRE)-- Andersen Global is proud to announce an expanded presence in Mozambique as collaborating firm, Isálcio Mahanjane Advogado & Associados, opens a new office in the city of Beira. Isálcio Mahanjane Advogado & Associados, which also has a presence in Maputo, became a collaborating firm in August 2018.

Led by Managing Partner Isálcio Mahanjane, the firm specializes in providing quality services in all areas of law serving corporations and individuals. These services include commercial and corporate law, banking and finance law, labor law, real estate management, oil and gas, and mining law and administrative litigation.

“The addition of a location in Beira reinforces our reputation as a leading firm that provides clients with the best-in-class services and is the next step for us as we continue expanding throughout Mozambique,” said Isálcio. “Our ultimate goal is to have a location in every major province within the country.”

Andersen Global is an international association of legally separate, independent member firms comprised of tax and legal professionals around the world. Established in 2013 by U.S. member firm Andersen Tax LLC, Andersen Global now has more than 5,000 professionals worldwide and a presence in over 165 locations through its member firms and collaborating firms.

View source version on businesswire.com: https://www.businesswire.com/news/home/20191203005108/en/

Contacts

Megan Tsuei
Andersen Global
415-764-2700

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Everbridge Selected to Power Countrywide Disaster Alert Platform in Peru for 37 Million Residents and Annual Visitors

 Peru Win Reinforces Everbridge’s Global Leadership in Population Alerting with Countrywide Contracts in the Americas, EMEA, and APAC regions



BURLINGTON, Mass.-Wednesday 4 December 2019 [ AETOS Wire ]

(BUSINESS WIRE)-- Everbridge, Inc. (NASDAQ: EVBG), the global leader in critical event management, today announced it has been selected by Peru’s Ministry of Transportation and Communications (MTC) to power the nation’s Sistema de Mensajería de Alerta Temprana de Emergencia (Sismate), Peru’s Early Warning Emergency Messaging System. The news marks the completion of contract negotiations with the MTC that Everbridge had initially disclosed in September, without naming the country. The win reinforces Everbridge’s position as the global leader in population warning systems with contracts in the Americas, EMEA, and APAC regions.

After the Sismate is deployed, it will be activated once Peru’s National Institute of Civil Defense detects a major incident. The system, powered by Everbridge Public Warning, will send critical messages to mobile phones before, during and after the emergency. Sismate alerts can also be used in drills and to provide support in search and rescue operations. The Sismate is designed to serve over 37 million people including Peru’s 33 million residents and 4 million annual visitors.

“This technology marks a milestone in risk and disaster management at the national level, which will be consolidated by combining joint efforts between various institutions and citizens,” explained Deputy Minister of Communications Virginia Nakagawa to El Economista.

“Everbridge is honored to support Peru with its national warning system,” said David Meredith, Chief Executive Officer at Everbridge. “Peru joins a growing number of countries that have chosen to partner with Everbridge to implement a nationwide system to protect their population and visitors amid an escalating threat environment.”

The Everbridge Platform has been deployed by more local, state, and national governments across the globe than any other solution, offering the ability to reach over 500 million people in more than 200 countries. In addition to Peru, Everbridge Public Warning has been deployed to reach the mobile populations on a country-wide scale in Sweden, Iceland, the Netherlands, Singapore, Greece, and a number of the largest states in India, and is currently being implemented in Australia. Everbridge is the first population alerting provider to support four EU countries in conjunction with the recent EU mandate requiring member countries to have a population-wide alerting system in place by June 2022.

Everbridge Public Warning represents the only multichannel solution which allows countries to deploy their preferred combination of emergency communications methods. The Everbridge population warning system communicates across all phases of an incident, leverages location intelligence (static location, last known location, and expected location), provides directed two-way communications, and enables countries to combine both speed of delivering alerts with the broadest reach to cover the full population and visitors.

About Everbridge

Everbridge, Inc. (NASDAQ: EVBG) is a global software company that provides enterprise software applications that automate and accelerate organizations’ operational response to critical events in order to keep people safe and businesses running. During public safety threats such as active shooter situations, terrorist attacks or severe weather conditions, as well as critical business events including IT outages, cyber-attacks or other incidents such as product recalls or supply-chain interruptions, over 4,800 global customers rely on the company’s Critical Event Management Platform to quickly and reliably aggregate and assess threat data, locate people at risk and responders able to assist, automate the execution of pre-defined communications processes through the secure delivery to over 100 different communication devices, and track progress on executing response plans. The company’s platform sent over 2.8 billion messages in 2018 and offers the ability to reach over 500 million people in more than 200 countries and territories, including the entire mobile populations on a country-wide scale in Australia, Sweden, the Netherlands, Singapore, Greece, and a number of the largest states in India. The company’s critical communications and enterprise safety applications include Mass Notification, Incident Management, Safety Connection™, IT Alerting, Visual Command Center®, Public Warning, Crisis Management, Community Engagement™ and Secure Messaging. Everbridge serves 9 of the 10 largest U.S. cities, 8 of the 10 largest U.S.-based investment banks, 46 of the 50 busiest North American airports, 6 of the 10 largest global consulting firms, 6 of the 10 largest global auto makers, all 4 of the largest global accounting firms, 9 of the 10 largest U.S.-based health care providers, and 5 of the 10 largest U.S.-based health insurers. Everbridge is based in Boston and Los Angeles with additional offices in Lansing, San Francisco, Beijing, Bangalore, Kolkata, London, Munich, Oslo, Singapore, Stockholm and Tilburg. For more information, visit www.everbridge.com, read the company blog, and follow on LinkedIn, Twitter, and Facebook.

Cautionary Language Concerning Forward-Looking Statements

This press release contains “forward-looking statements” within the meaning of the “safe harbor” provisions of the Private Securities Litigation Reform Act of 1995, including but not limited to, statements regarding the anticipated opportunity and trends for growth in our critical communications and enterprise safety applications and our overall business, our market opportunity, our expectations regarding sales of our products, our goal to maintain market leadership and extend the markets in which we compete for customers, and anticipated impact on financial results. These forward-looking statements are made as of the date of this press release and were based on current expectations, estimates, forecasts and projections as well as the beliefs and assumptions of management. Words such as “expect,” “anticipate,” “should,” “believe,” “target,” “project,” “goals,” “estimate,” “potential,” “predict,” “may,” “will,” “could,” “intend,” variations of these terms or the negative of these terms and similar expressions are intended to identify these forward-looking statements. Forward-looking statements are subject to a number of risks and uncertainties, many of which involve factors or circumstances that are beyond our control. Our actual results could differ materially from those stated or implied in forward-looking statements due to a number of factors, including but not limited to: the ability of our products and services to perform as intended and meet our customers’ expectations; our ability to attract new customers and retain and increase sales to existing customers; our ability to increase sales of our Mass Notification application and/or ability to increase sales of our other applications; developments in the market for targeted and contextually relevant critical communications or the associated regulatory environment; our estimates of market opportunity and forecasts of market growth may prove to be inaccurate; we have not been profitable on a consistent basis historically and may not achieve or maintain profitability in the future; the lengthy and unpredictable sales cycles for new customers; nature of our business exposes us to inherent liability risks; our ability to attract, integrate and retain qualified personnel; our ability to successfully integrate businesses and assets that we may acquire; our ability to maintain successful relationships with our channel partners and technology partners; our ability to manage our growth effectively; our ability to respond to competitive pressures; potential liability related to privacy and security of personally identifiable information; our ability to protect our intellectual property rights, and the other risks detailed in our risk factors discussed in filings with the U.S. Securities and Exchange Commission (“SEC”), including but not limited to our Annual Report on Form 10-K for the year ended December 31, 2018 filed with the SEC on March 1, 2019. The forward-looking statements included in this press release represent our views as of the date of this press release. We undertake no intention or obligation to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise. These forward-looking statements should not be relied upon as representing our views as of any date subsequent to the date of this press release.

All Everbridge products are trademarks of Everbridge, Inc. in the USA and other countries. All other product or company names mentioned are the property of their respective owners.

View source version on businesswire.com: https://www.businesswire.com/news/home/20191202005296/en/

Contacts

Media:
Jim Gatta
Everbridge
jim.gatta@everbridge.com
215-290-3799

Jeff Young
Everbridge
jeff.young@everbridge.com
781-859-4116



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Moody’s Analytics Experts Release New Book on Future of Credit Risk

Credit Risk Measurement and Management: Disruption and Evolution, edited by Amnon Levy and Jing Zhang, traces the evolution of credit risk management, with contributions from economist Nouriel Roubini, KMV and DCI co-founder Stephen Kealhofer, Prudential CRO Nick Silitch, and other leading thinkers.




SAN FRANCISCO-Tuesday 3 December 2019 [ AETOS Wire ]

(BUSINESS WIRE)-- Moody’s Analytics, a leading provider of financial intelligence, today announced the release of Credit Risk Measurement and Management: Disruption and Evolution, edited by Moody’s Analytics experts Dr. Amnon Levy, Head of Portfolio and Balance Sheet Research, and Dr. Jing Zhang, Global Head of Research and Modeling. Other Moody’s Analytics experts contributing to the book include Dr. Douglas Dwyer, Dr. Tony Hughes, Dr. Ashit Talukder, Elaine Wong, and Dr. Pierre Xu.

Published by Risk Books, this book includes 15 chapters representing a broad selection of perspectives from key thinkers and practitioners involved in credit risk management. Contributors hail from regulatory bodies, banks, insurance companies, consulting firms, analytics providers, and fintech disruptors. Their contributions explore the intersection of technology, regulatory mandates, and geopolitical developments, and form conclusions about the business and operational impacts of each.

”Over the last few decades, regulatory oversight, information-technology advances, and political events have driven unprecedented levels of change in credit risk management,” said Levy. “Organizations will need to understand the interplay among these forces to manage credit risk effectively both now and in the coming years.”

“The future of credit risk management will be marked by seemingly intractable new challenges, including climate change and global debt,” added Zhang. “But by studying the evolution of credit risk management to this point, institutions will be better prepared to handle these threats going forward.”

Click here to learn more about the book or to purchase a copy.

About Moody’s Analytics

Moody’s Analytics provides financial intelligence and analytical tools to help business leaders make better, faster decisions. Our deep risk expertise, expansive information resources, and innovative application of technology help our clients confidently navigate an evolving marketplace. We are known for our industry-leading and award-winning solutions, made up of research, data, software, and professional services, assembled to deliver a seamless customer experience. We create confidence in thousands of organizations worldwide, with our commitment to excellence, open mindset approach, and focus on meeting customer needs. For more information about Moody’s Analytics, visit our website or connect with us on Twitter and LinkedIn.

Moody's Analytics is a subsidiary of Moody's Corporation (NYSE: MCO). Moody’s Corporation reported revenue of $4.4 billion in 2018, employs approximately 13,200 people worldwide and maintains a presence in 44 countries.

View source version on businesswire.com: https://www.businesswire.com/news/home/20191105005145/en/

Contacts
GENE KIM
Moody’s Analytics Communications
+1.415.874.6013

Moody’s Analytics Media Relations

moodysanalytics.com
twitter.com/moodysanalytics
linkedin.com/company/moodysanalytics




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Gen Re and PAI Health Take Strategic Partnership to Next Level

Exclusivity agreement demonstrates joint commitment to bringing pioneering digital heart health technology to insurance community.

STAMFORD, Conn.-Tuesday 3 December 2019 [ AETOS Wire ]

(BUSINESS WIRE)-- Decades of evidence have proven cardiorespiratory fitness to be a leading predictor of longevity and future health. Yet it is one that has been largely overlooked within insurance customer health profiles. With the signing of the exclusive agreement between leading global reinsurer, Gen Re, and health technology software company, PAI Health, this is set to change.

PAI Health is known for its innovation in biometric sensing and algorithm development with unique data insights rooted in cardiorespiratory fitness. The company’s digital services are based on published research that has demonstrated the effectiveness of the heart rate-based metric called Personal Activity Intelligence (PAI) in recommending personalized activity levels for optimal mortality risk reduction from cardiovascular disease and other lifestyle diseases.

Over the past 18 months, Gen Re and PAI Health have been working together to tailor the PAI proposition for the insurance sector. Together, they have now begun showcasing its potential to Gen Re’s clients around the world, with a view to using PAI’s potential to drive customer engagement and explore new ways of assessing risk.

Commenting on the agreement, Winfried Heinen, Head of Gen Re Life/Health International, said: “We meet many insurtech companies with promising ideas but PAI Health stood out from the start due to the scientific rigour behind their solution. We have no doubt about the value PAI holds for the insurance community, both in terms of acquisition and engagement, and ultimately helping consumers lead longer and healthier lives.”

Vincent DeMarco, Head of Gen Re’s North American Life/Health Division, added: “The signing of this agreement demonstrates our mutual commitment to bringing PAI Health’s pioneering mHealth technology to insurance. We look forward to working closely with them to build on the momentum already created.”

Speaking on behalf of PAI Health, Chief Commercial Officer Sally Powell said: “PAI Health’s global strategic partnership with Gen Re comes at the right time as the insurance industry is being challenged by customers to provide digital health solutions that are highly personalised and provide health protection day to day. Gen Re’s global presence combined with our unique solutions makes us ideal partners to co-develop digital insurance solutions that provide significant value to insurers and their policyholders.”

Hear more about the science behind PAI from inventor Ulrik Wisløff, Professor at NTNU and Head of the Cardiac Exercise Research Group, in conversation with Gen Re’s Ross Campbell. Link to 5 min video
PAI Health is one of a selection of hand-picked insurtech companies Gen Re is working with to develop insurance products and solutions that meet the needs and expectations of consumers in the digital age. Contact us to find out more about our digital activities and to arrange an introduction.

About Gen Re

Gen Re delivers reinsurance solutions to the Life/Health and Property/Casualty insurance industries. We work closely with our clients to understand their strategic and operational goals, offering a wide range of products, tools and resources that aim to promote our clients’ ongoing growth and success.

Gen Re is a member of the Berkshire Hathaway family of companies and has earned superior financial strength ratings from each of the major rating agencies. We take our commitments very seriously. With $14.4 billion in capital and $9.7 billion in premiums, we only make promises we can keep. www.genre.com

About PAI Health

PAI Health is a health technology company that offers unique data insights rooted in the proven science of cardiorespiratory fitness. The company’s suite of digital tools help insurers increase engagement, drive new customer acquisition and reduce costs. PAI (Personal Activity Intelligence) is the first scientifically validated and published score that prescribes a personalised level of activity to optimize an individual’s cardiorespiratory fitness to reduce the risk of cardiovascular and other lifestyle diseases. www.paihealth.com

View source version on businesswire.com: https://www.businesswire.com/news/home/20191203005076/en/

Contacts
Media Contact:
Sabine Denné, Head of Global Marketing & Client Communications, email: denne@genre.com

Product Contacts:
International: Ross Campbell, Life/Health Chief Underwriter R&D, email: ross_campbell@genre.com

North America: Ammon Dixon, Life/Health Strategic Initiative Projects Leader, email: ammon.dixon@genre.com

PAI Health Contact:
Tricia Burton, VP, Marketing, email: tricia.burton@paihealth.com

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Octapharma announces the presentation of the final results from the NuProtect study of Nuwiq® (simoctocog alfa) in previously untreated patients (PUPs) at ASH 2019

LACHEN, Switzerland-Tuesday 3 December 2019 [ AETOS Wire ]

(BUSINESS WIRE)-- Octapharma has announced that the final results of the NuProtect study will be presented by Dr Ri Liesner (Great Ormond Street Hospital for Children, London, UK) as an oral presentation at the 61st Annual Meeting of the American Society of Hematology (ASH) 2019 in Orlando, Florida.

Dr Liesner commented that “I am excited to be representing the NuProtect study group to share these data. The data should help to inform clinical decision-making and provide valuable evidence to reassure clinicians and patients that Nuwiq® is an effective treatment option for PUPs”.

The NuProtect study is the largest prospective study of a single FVIII concentrate in true PUPs with haemophilia A. The study assessed the immunogenicity, efficacy and safety of the human cell line-derived recombinant FVIII Nuwiq® (simoctocog alfa) in 108 PUPs. Final results on the immunogenicity, efficacy and safety of Nuwiq® will be shared for the first time at an oral presentation on Monday 9th December.

“We are proud to present these important data in PUPs, which showcase the clinical features of Nuwiq® founded on its human cell line origin” said Larisa Belyanskaya, Head of IBU Haematology at Octapharma. Olaf Walter, Board Member at Octapharma, added that “The NuProtect study data add to the growing portfolio of clinical experience with Nuwiq® and support our goal at Octapharma to improve the lives of people with bleeding disorders”.

About Nuwiq®
Nuwiq® (simoctocog alfa) is a 4th generation recombinant factor VIII (rFVIII) protein, produced in a human cell line without chemical modification or fusion with any other protein1. It is cultured without additives of human or animal origin, is devoid of antigenic non-human protein epitopes and has a high affinity for von Willebrand factor1. Nuwiq® treatment has been assessed in seven completed clinical trials which included 201 previously treated patients (PTPs; 190 individuals) with severe haemophilia A, including 59 children1. Treatment of previously untreated patients (PUPs) with Nuwiq® was assessed in the NuProtect study. In an interim analysis of 66 patients, the cumulative incidence of high-titre inhibitors was 12.8%, and the cumulative incidence of all inhibitors was 20.8%2. Nuwiq® is available in 250 IU, 500 IU, 1000 IU, 2000 IU, 2500 IU, 3000 IU and 4000 IU presentations3. Nuwiq® is approved in 59 countries for use in the treatment and prophylaxis of bleeding in patients with haemophilia A (congenital FVIII deficiency) across all age groups3.

About the NuProtect study
The NuProtect study (NCT01712438) was a prospective, multicentre, multinational, open-label, non-controlled phase III study to assess the immunogenicity, efficacy and safety of Nuwiq® in patients with severe haemophilia A and without any previous exposure to FVIII concentrates or blood products containing FVIII. Patients were treated with Nuwiq® for 100 exposure days or up to 5 years. The study was conducted at 38 sites in 17 countries. A total of 110 patients were enrolled. Of these, 108 patients were treated with Nuwiq®.

About Haemophilia A
Haemophilia A is an X-linked hereditary bleeding disorder caused by a deficiency of factor VIII (FVIII) which, if left untreated, may lead to haemorrhages in muscles and joints and consequently to arthropathy and severe morbidity. The disorder affects around one in every 10,000 males worldwide. Prophylaxis with replacement FVIII therapy reduces the number of bleeding episodes and the risk of permanent joint damage.

About Octapharma
The vision of Octapharma is: “Our passion drives us to provide new health solutions advancing human life”. Headquartered in Lachen, Switzerland, Octapharma is one of the largest human protein manufacturers in the world, developing and producing human proteins from human plasma and human cell lines. As a family-owned company, Octapharma believes in investing to make a difference in people’s lives and has been doing so since 1983; because it’s in our blood. Our company values are Ownership, Integrity, Leadership, Sustainability and Entrepreneurship.

In 2018, the Group achieved €1.8 billion in revenue, an operating income of €346 million and invested €240 million into R&D and in capital expenditures in order to ensure future prosperity. Octapharma employs 8,314 people worldwide to support the treatment of patients in 115 countries with products across three therapeutic areas:

    Haematology (coagulation disorders)
    Immunotherapy (immune disorders)
    Critical care (bleeding management and functional volume replacement)

Octapharma has seven R&D sites and six state-of-the-art manufacturing facilities in Austria, France, Germany, Mexico and Sweden.

1. Lissitchkov T et al. Ther Adv Hematol 2019; doi: 10.1177/2040620719858471.
2. Liesner R et al. Haemophilia 2018; 24:211-20.
3. Nuwiq® Summary of Product Characteristics.

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Contacts

Octapharma AG Contacts:

Octapharma AG International Business Unit - Haematology
Olaf Walter
Olaf.Walter@octapharma.com

Larisa Belyanskaya
Larisa.Belyanskaya@octapharma.com
Tel: +41 55 4512121

Ivana Spotakova
Communications Manager
ivana.spotakova@octapharma.com
Tel.: +41793474607



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