Thales Completes the Acquisition of Imperva, Creating a Global Leader in Cybersecurity

 

 

• Combination creating one of the world’s 5 leading companies focused on protecting the heart of the digital ecosystem: applications, data and identities
• With the integration of Imperva starting in January, Thales will help organizations discover and protect sensitive data anywhere, manage access and secure all paths to it
• North America is now the second largest country of operations for Thales
• Imperva is Thales’ ninth acquisition in the digital security area over the last nine years, and the second largest in the Group's history after Gemalto

 

(BUSINESS WIRE) -- Thales (Euronext Paris: HO) announces today that it has completed the acquisition of Imperva, earlier than expected (previously foreseen at the beginning of 2024). This is a key milestone for Thales, creating a global leader in cybersecurity, with more than 5,800 cybersecurity experts across 68 countries and €2.4bn in cybersecurity revenue expected in 2024, including civil and defence activities, with double-digit growth expected thereafter. This transaction will generate significant value creation for Thales’ shareholders in line with the targets communicated in July 2023, when announcing the acquisition. In addition, the profile of Thales’ Digital Identity and Security (DIS) activity will be significantly enhanced with new financial targets by 2027 (2024-2027 organic sales growth of +6 to +7% and 2027 EBIT margin at 16.5%).

Patrice Caine, Chairman and Chief Executive Officer of Thales, said: “The acquisition of the US company Imperva is an important day for Thales, as it marks a new step in the expansion of our global cybersecurity capabilities for enterprises and governments around the world. We are very excited to welcome the Imperva teams to Thales. The combination of our entities' values and our joint commitment to a future of trust will create significant synergies, business opportunities and major market innovations. With ever-increasing cyber threats against business and government digital infrastructure, Thales is now uniquely positioned to help customers protect the heart of their digital ecosystem: applications, data and identities.”

Data-Centric Security spanning across Applications, Data and Identities

Together, Thales and Imperva will help customers address cybersecurity challenges that have increased rapidly in frequency, severity, and complexity, with the most comprehensive solutions for the broadest range of application, data security, and identity use cases. These three market segments combined are forecasted to grow significantly in the coming years. According to analysts’ forecast, worldwide end-user spending is projected to total around $20 billion in 2024.

With the addition of Imperva, Thales’ expanded cybersecurity portfolio now offers a highly complementary combination of solutions to help customers secure applications, data and identities across their entire digital ecosystem:

• Application Security: Unified protection for every application and API in the cloud, on-premises, or in a hybrid model. The market leading product suite includes Web Application Firewall (WAF), Distributed Denial of Service attack (DDoS) Protection, Advanced Bot Protection, Application Programming Interface (API) Security, a developer-friendly Content Delivery Network (CDN), and Runtime Application Self-Protection (RASP).

• Data Security: Protection and control of access to sensitive data anywhere whether at rest, in motion or in use. The product suite includes the CipherTrust Data Security Platform, Imperva Data Security Fabric, as well as the Luna and payShield Hardware Security Modules, often used as the root of trust for cryptographic operations.

• Identity & Access Management: seamless, secure and trusted access to applications and digital services for customers, employees and partners. The product suite includes the OneWelcome Identity Platform and SafeNet Trusted Access.

“As a long-standing partner of both Thales and Imperva, we at Exclusive Networks are delighted with the combination of two companies that we know and value,” said Jesper Trolle, CEO Exclusive Networks. “This acquisition marks a key step in Thales' ambition to become a global leader in cybersecurity, reinforcing its strength in data security and expanding into the buoyant application security market. With this new combined value proposition, Thales will be uniquely positioned to offer even more innovative and effective solutions to address the growing security and compliance challenges faced by organisations around the world.”

This is Thales’ ninth acquisition in the digital security area over the last nine years, and the second largest in the Group's history after Gemalto, world leader in digital security. After the completed acquisitions of Tesserent, the leading player in cybersecurity in Australia, S21sec & Excellium, two major players in cybersecurity consulting, integration and managed services in Europe, and OneWelcome, a European leader in Customer Identity and Access Management, the integration of Imperva within Thales will position the Group’s cybersecurity business as one of the top 5 global leaders in cybersecurity.

Thales in North America

With 6,200 employees1 and €2.4 billion revenues2 in North America in 2022, and approximately 50% of the free float shares held by U.S. shareholders, Thales already has a strong presence in the region. The acquisition of Imperva increases Thales’ digital security workforce in North America by almost a third.

Each year, Thales invests €4 billion in R&D, of which €1 billion is self-financed3. The Group is fully committed to supporting Imperva’s customers and augmenting its solutions through accelerated innovations. As an innovator, Thales has a total of 20,000 patents in its portfolio, more than 50% of these involve key technologies related to AI, generative artificial intelligence, cybersecurity, big data, the cloud, augmented reality and quantum technologies.

About Thales   Thales (Euronext Paris: HO) is a global leader in advanced technologies within three domains: Defence & Security, Aeronautics & Space, and Digital Identity & Security. It develops products and solutions that help make the world safer, greener and more inclusive.   The Group invests close to €4 billion a year in Research & Development, particularly in key areas such as quantum technologies, Edge computing, 6G and cybersecurity.   Thales has 77,000 employees4 in 68 countries. In 2022, the Group generated sales of €17.6 billion.

PLEASE VISIT

Thales Group
Security
https://cpl.thalesgroup.com/about-us/thales-imperva

_____________
1 Including GTS employees
2 Without GTS revenues
3 Group-level data
4 Excluding the Transport business, which is currently being divested

 

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Contacts

Head of Media Relations
Cédric Leurquin
+33 (0)6 31 01 53 25
cedric.leurquin@thalesgroup.com

Thales, Media Relations
Security
Marion Bonnet
+33(0)6 60 38 48 92
marion.bonnet@thalesgroup.com

Abdulaziz Al-Gudaimi, Aramco Veteran, Joins EIG as Senior Advisor and Chairman of MENA Operations

 WASHINGTON - Friday, 01. December 2023

(BUSINESS WIRE) -- EIG, a leading institutional investor in the global energy and infrastructure sectors, today announced that Abdulaziz Al-Gudaimi has joined EIG as Senior Advisor and Chairman of EIG’s Middle East & North Africa (“MENA”) Operations. Mr. Al-Gudaimi, formerly Executive Vice President of Corporate Development at Saudi Aramco (“Aramco”), has over 38 years of experience in energy markets and will provide strategic counsel to EIG on its investment activities and continued growth in the region.

“We are thrilled to welcome Abdulaziz to the firm,” said R. Blair Thomas, EIG Chairman and CEO. “His deep sector expertise and wealth of experience in MENA will be instrumental for EIG in sourcing additional investment opportunities across critical energy and energy-related infrastructure, and for our portfolio companies as they navigate the complex challenges of transitioning to a low-carbon future.”

“I have come to know Blair and the EIG team through the firm’s partnership with Aramco and am eager to build on their success in the region,” said Mr. Al-Gudaimi. “As the energy transition continues in importance and paves the way for a better tomorrow, EIG is well positioned to find opportunities to leverage its operational expertise and bolster the decarbonization of the region’s energy sector. I look forward to helping create value for the firm’s portfolio companies and its investors.”

Mr. Al-Gudaimi served as Executive Vice President of Corporate Development at Aramco before retiring from the position in December 2022. In this role, he helped Aramco secure greater access to growth markets and technologies through portfolio optimization and strategic alignment. Mr. Al-Gudaimi previously held several other leadership positions at Aramco, including Senior Vice President of Downstream and Vice President of Power Systems. Mr. Al-Gudaimi currently serves as a Director of Vision Invest Holding and Saudi Alfransi Bank and previously served as Chairman of the Boards of Motiva Enterprises LLC, Arlanxeo, Saudi Aramco Total Refining and Petrochemical Company, Aramco Trading Company and Petro Rabigh. He holds a BS in Petroleum Engineering and a Master of Business Administration.

About EIG

EIG is a leading institutional investor in the global energy and infrastructure sectors with $23.0 billion under management as of September 30, 2023. EIG specializes in private investments in energy and energy-related infrastructure on a global basis. During its 41-year history, EIG has committed over $45.9 billion to the energy sector through over 400 projects or companies in 42 countries on six continents. EIG’s clients include many of the leading pension plans, insurance companies, endowments, foundations and sovereign wealth funds in the U.S., Asia and Europe. EIG is headquartered in Washington, D.C. with offices in Houston, London, Sydney, Rio de Janeiro, Hong Kong and Seoul.

 

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Media

FGS Global

Kelly Kimberly / Brandon Messina

+1 212-687-8080

EIG@fgsglobal.com

 

IFRC-DREF calls on global donors to help the world ‘Stand Tall’ in the face of accelerating humanitarian need - supporting smarter and faster disaster relief

 

(BUSINESS WIRE) -- The International Federation of Red Cross and Red Crescent Societies (IFRC) has launched a new campaign to address rapidly escalating climate driven humanitarian crises. It calls on global governments and international donors to support local emergency responders and disaster hit communities - helping them to Stand Tall with smarter and faster humanitarian funding.

The IFRC’s Disaster Response Emergency Fund (IFRC-DREF) is the quickest, most efficient and most transparent way of getting funding directly to local National Societies — both before and immediately after a crisis hits. Yet it faces growing pressure to anticipate and respond to multiple, simultaneous and complex crises around the world as a result of climate change.

Today, 3.6 billion people live in areas highly susceptible to climate change. Humanitarian funding needs are growing as more people are adversely impacted by climate-related disasters each year. The signs are hard to ignore: IFRC-DREF funding allocation increased by 75% to meet escalating demands in the first half of 2023 compared to the same period in 2022 - predominately in response to floods and earthquakes.

Shoulder to shoulder - to Stand Tall

The Stand Tall campaign calls on global governments and private donors to stand shoulder to shoulder with local emergency responders and the communities they support. Stand Tall aims to grow the humanitarian funds available to on-the-ground relief organisations from the CHF 64 million (US$73 million) available today to CHF 100 million (US$114 million) by 2025.

Coinciding with COP28, IFRC’s Stand Tall campaign uses a series of visuals to champion the incredible network of donors, volunteers, and impacted communities that make up IFRC-DREF.

Nena Stoiljkovic, Under-Secretary General at IFRC, said: “In the battle against climate change, we have reached a critical juncture – funding needs outstrip supply as communities face more and more devastating impact. Our funding partners for IFRC-DREF enable us to deliver local response with global support.

“We take a moment to celebrate the incredible work and accomplishments of our inspiring network of funding partners and volunteers in impacted communities. We are proud of their determination and collaboration as we strive to prevent and lessen the burden of climate disasters on vulnerable communities. We encourage our partners to keep supporting IFRC-DREF’s action. Together, we will Stand Tall in the face of climate disasters.”

Smarter and faster funding - to those who need it, when they need it

Unlike other humanitarian funding mechanisms, 82% of IFRC-DREF funds go directly to National Societies supporting local action – compared with a global average of just 1.2%. Localised, community-led action is key to ensuring communities are equipped to prepare for, and overcome, devastating crises.

IFRC-DREF is evolving as it works to increase the impact of every donation to the fund. In September 2023, for example, IFRC announced the launch of IFRC-DREF Insurance - a truly innovative way to ensure that funding is always there for those who need it, when they need it. It acts as a back-stop to IFRC-DREF, bringing an additional CHF 20 million (c US $23 million) on stream, triggered during periods of high demand.

In helping to reach the CHF 100 million target by 2025, global governments and private donors can Stand Tall with emergency responders and their communities - saving lives and livelihoods in the face of climate driven disasters.

To learn more about IFRC-DREF and how donors can support its 2025 ambition, visit ifrc.org.

About the International Federation of the Red Cross and Red Crescent Societies (IFRC)

IFRC is the world’s largest humanitarian network, comprising 191 National Societies and bringing together more than 16 million volunteers working to save lives, build community resilience, strengthen localisation and promote dignity around the world.

About the IFRC’s Disaster Response Emergency Fund (IFRC-DREF)

Established in 1979, the IFRC-DREF is the quickest, most efficient, and most transparent mechanism for donors to channel global short-term emergency funding directly for local community-based action. While the average of international humanitarian funds directly channelled to local actors every year lies around 1.2% globally, 82% of IFRC-DREF’s allocation is directly transferred to the National Societies. Since its inception, more than 220 million people in crisis worldwide have benefited from IFRC-DREF support.

 

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For more information:

To request an interview, contact: media@ifrc.org

LTIMindtree Partners with Metasphere to Deliver Smart Sewers Solutions

 LONDON & MUMBAI, India - Thursday, 30. November 2023

(BUSINESS WIRE) -- LTIMindtree [NSE: LTIM, BSE: 540005], a global technology consulting and digital solutions company, announced that it has been selected as a strategic partner by Metasphere, a wastewater application specialist, to scale their Smart Sewers management platform. As a part of this engagement, LTIMindtree will transform Metasphere’s next-generation wastewater monitoring solution portfolio, and enable scalable delivery and platform to their customers.

Metasphere, part of Grundfos, provides smart network management solutions to the global utility industry. The company helps customers prevent leaks and spills for a cleaner, greener world and has deployed more than 200K sensors for their customers worldwide. By leveraging cutting-edge technology, the company offers intelligent, innovative, all-in-one wastewater application solutions. These solutions provide full network visibility, performance and forecasting that reduce telemetry ownership cost for customers to manage time-critical remote assets and system.

Sudhir Chaturvedi, President and Executive Board Member, LTIMindtree, said, “We are excited to partner with Metasphere, a Grundfos company, in their modernization program. With increasing focus on utilities worldwide, it has become critical to improve service delivery, reduce accidents and deliver real-time insights to customers. After careful consideration by our team of experts, LTIMindtree took Metasphere's cloud architecture and optimized it for AWS scale and cost. This transformation is enabling Metasphere in optimizing up to 25% of the total cost, while delivering almost unlimited scale and enhanced performance.”

Tim O’Brien, Chief Executive Officer, Metasphere, said, “This engagement is key to our ability to deliver modern, scalable solutions to all our utility clients worldwide. In LTIMindtree, we found an expert partner to support our diverse needs and bring in additional innovative offerings that we can integrate in our system in the future. We are confident that this partnership will bring us closer to our vision of leveraging our solutions to serve at least 10% of world’s population by 2040.”

The modernised solutions designed by LTIMindtree and built on AWS have significantly reduced Metasphere’s customer onboarding time from days to minutes and activated faster rollout of new features.

Paddy Fitzpatrick, UKI ISV Head, AWS, said, “We are excited to see organisations like LTIMindtree deliver innovative solutions for the water industry by building on AWS. This collaboration between LTIMindtree and Metasphere will give the utility industry access to new solutions such as real-time network visibility and wastewater monitoring to help reduce costs and enhance performance. Together, we can help the utility industry leverage the power of cloud to drive business value.”

About LTIMindtree:

LTIMindtree is a global technology consulting and digital solutions company that enables enterprises across industries to reimagine business models, accelerate innovation, and maximize growth by harnessing digital technologies. As a digital transformation partner to more than 700 clients, LTIMindtree brings extensive domain and technology expertise to help drive superior competitive differentiation, customer experiences, and business outcomes in a converging world. Powered by 83,000+ talented and entrepreneurial professionals across more than 30 countries, LTIMindtree — a Larsen & Toubro Group company — combines the industry-acclaimed strengths of erstwhile Larsen and Toubro Infotech and Mindtree in solving the most complex business challenges and delivering transformation at scale. For more information, please visit https://www.ltimindtree.com/.

About Metasphere:

Metasphere is a global industry brand, synonymous with telemetry excellence to help our customers prevent leaks and spills for a cleaner, greener world. As a wastewater application specialist business, we provide monitoring solutions to the global utility industry with installations in more than 25 major utilities, government agencies and system integrators. We liaise with all sectors of the industry, from major utility companies to environmental and regulatory bodies. With operations in the UK and Australia, our friendly expert team is always ready to help with your telemetry and monitoring needs, whether relating to water, wastewater, environment or gas. For more information, please visit https://www.metasphere.co.uk/.

 

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Contacts

LTIMindtree Media Contact: Shambhavi Revandkar | shambhavi.revandkar@ltimindtree.com
Metasphere Media Contact: Ret Mathieson | ret.mathieson@metasphere.co.uk

 

QPS Holdings, LLC Expands Operations in Springfield, Missouri

 (BUSINESS WIRE) -- QPS Holdings, LLC, a global contract research organization has expanded operations in Springfield, Missouri. The new facilities include a clinical (safety) laboratory, an updated self-contained pharmacy, and a new dedicated space to build and ship clinical trial kits. The 2,750-square-foot facility is fully operational as of the fall of 2023 and will give QPS significant flexibility in clinical research study operations.

The state-of-the art laboratory is equipped with the most up-to-date technologies for Chemistry, Urinalysis, Serology, Coagulation, and Hematology testing, designed to monitor subject safety during ongoing clinical trials. The updated pharmacy now houses multiple fully certified pharmacists and compounding facilities, and the clinical trial kit facility can pick, pack and ship orders anywhere in the world, usually within 24 hours.

“QPS Missouri continues to expand and offer new services in Springfield, and the addition of a safety lab, the updated pharmacy and the clinical trial kit production area were the next steps to enhance our capabilities to provide comprehensive clinical trial services to the local Springfield community,” stated Brendon Bourg, QPS Missouri Vice President, Early Phase Clinical and Head of Administration. “Adding this new safety lab to our local clinical trial facility means that our physicians can receive laboratory results in real-time, adding an additional level of safety for participants. In addition, QPS can now offer these new clinical trial capabilities to our valued clients.”

Over the next few years, Bourg expects these new facilities to grow from providing services for clinical trials running in the Springfield facility, into providing central laboratory, pharmacy, and clinical trial kit-building services for multi-site clinical research projects, expanding the value of the services provided to all QPS clients.

ABOUT QPS HOLDINGS, LLC

QPS Holdings, LLC, is a global clinical research organization (CRO), that supports the preclinical, bioanalytical, and clinical development of new pharmaceutical products. It is headquartered in Newark, Delaware, and has 7 clinical research and development sites that house a mix of preclinical, bioanalytical, and clinical trials research facilities. These sites are in the USA (Delaware, Florida, and Missouri), The Netherlands, Taiwan, China, and India. To learn more about QPS Holdings, LLC, visit https://www.qps.com.

QPS Missouri is a QPS Holdings, LLC flagship clinical site in Springfield, Missouri, USA. The Springfield campus houses 5 independent clinics with over 240 Phase I clinical trial beds, multiple laboratories, a 2,500 square foot negative pressure room, a pharmacy with a clean room, and a new Screening and Recruitment Center. Since opening its doors in Springfield in 1994, QPS Missouri has conducted over 2,100 FDA-regulated studies and paid out over $35 million to as many as 50,000 local participants. To learn more about QPS Missouri, visit https://www.417studies.com.

 

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Contacts

Trent Chance

417.831.2048

Trent.Chance@qps.com

https:/417studies.com

PUMA RE:SUEDE Pilot Project Turns Experimental Sneakers Into Compost

 HERZOGENAURACH, Germany - Wednesday, 29. November 2023



(BUSINESS WIRE)--Sports company PUMA showed that it can successfully turn an experimental version of its classic SUEDE sneaker into compost under certain tailor-made industrial conditions, as it announced the results of its two-year-long RE:SUEDE experiment.

In 2021, PUMA created 500 pairs of the experimental RE:SUEDE, using Zeology tanned suede, a TPE outsole and hemp fibres. The RE:SUEDEs were worn for half a year by volunteers in Germany to test the comfort and durability of the shoes before PUMA sent them to a specially equipped industrial composting area operated by its partner Ortessa Group in the Netherlands.

A special procedure had to be established to turn the shoes into compost. First, they were shredded and mixed with other green household waste and placed into a composting tunnel. They were then sprayed with leaching-water from earlier composting that contains nutrients and naturally heated due to the biological activity and controlled air circulation in the tunnel. After approximately 3.5 months, the materials that were small enough (<10mm) to pass through a sieve were sold as Grade A compost for agricultural use (within the standards of the Netherlands), while the remaining materials were returned to the composting tunnel until they too had broken down to the desired level (<10mm). Ortessa Group adhered to all legal requirements for compost applicable at their facilities in the Netherlands during this process.

“While the RE:SUEDE could not be processed under the standard operating procedures for industrial composting, the shoes did eventually turn into compost,” said Anne-Laure Descours, Chief Sourcing Officer at PUMA. “We will continue to innovate with our partners to determine the infrastructure and technologies needed to make the process viable for a commercial version of the RE:SUEDE, including a takeback scheme, in 2024.”

Transparency is another important pillar of the RE:SUEDE experiment, as PUMA will share its insights in a detailed report, so its peers and other interested stakeholders can learn from the experiment and apply the learnings to their own initiatives.

“We learned a lot during the RE:SUEDE trial and how to streamline our industrial composting process to include items that need longer to turn into compost,” said Marthien van Eersel Manager Materials & Innovations at Ortessa. “While all RE:SUEDE materials can decompose, the sole of the RE:SUEDE required more pre-processing and additional time in the composting tunnel to completely break down.”

As a result of the feedback received from the people who wore the RE:SUEDE for half a year, PUMA will improve the comfort of future versions of the shoes by enhancing the overall fit by using a new material pattern for the upper and the sock liner.

The RE:SUEDE experiment was the first programme, together with the novel polyester recycling programme RE:FIBRE, to launch as part of PUMA’s “Circular Lab”, an innovation hub led by PUMA’s innovation and design experts with the aim to create the future of the company’s circularity programmes.

For more information, please visit www.Foreverbetter.com and ortessa.com

PUMA

PUMA is one of the world’s leading sports brands, designing, developing, selling and marketing footwear, apparel and accessories. For 75 years, PUMA has relentlessly pushed sport and culture forward by creating fast products for the world’s fastest athletes. PUMA offers performance and sport-inspired lifestyle products in categories such as Football, Running and Training, Basketball, Golf, and Motorsports. It collaborates with renowned designers and brands to bring sport influences into street culture and fashion. The PUMA Group owns the brands PUMA, Cobra Golf and stichd. The company distributes its products in more than 120 countries, employs about 20,000 people worldwide, and is headquartered in Herzogenaurach/Germany.

Ortessa Group

Ortessa is a group of five enterprising waste companies: veyzle, Lammertyn.net, van Kaathoven, Rondo and Valor Composting. Together, the subsidiaries master all links of waste management, collection and processing and prove daily the power of smart partnering. Each with its own specialism in the field of waste, but with one clear joint mission: to be open about waste. With a realistic, pragmatic and results-oriented view, the Ortessa Group helps clients deal with waste challenges.

 

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Contacts

Samantha Du Plessis – PUMA SE – samantha.duplessis@puma.com

M. Schepers – Ortessa – communicatie@ortessa.com

Results From Galderma’s Phase IIIb Trials Demonstrate Rapid and Long-Lasting Effect of RelabotulinumtoxinA on Crow’s Feet and Frown Lines

 ZUG, Switzerland - Thursday, 30. November 2023

Both trials met their primary endpoints, demonstrating treatment with RelabotulinumtoxinA resulted in a statistically significant improvement in frown lines and crow’s feet.1,2

Results reinforce the rapid onset of action of RelabotulinumtoxinA, with some patients reporting improvement as early as day one in both trials.1,2

Results also underscore the durability of RelabotulinumtoxinA with at least a third of patients rating their frown lines as ‘improved’ or better through to month 12 in one study.2

Treatment was well tolerated and all treatment-related adverse events were reported as non-serious.1,2

 

(BUSINESS WIRE) -- Galderma announced today topline results from two phase IIIb trials investigating RelabotulinumtoxinA for the treatment of glabellar lines (GL – frown lines) and lateral canthal lines (LCL – crow’s feet). Both studies met their primary endpoints, demonstrating that RelabotulinumtoxinA, a novel liquid formulation botulinum toxin A, significantly improves both frown lines and crow’s feet, with a rapid onset of action as early as day one and long duration.1,2

 

“These results provide an additional layer of confidence in the long-lasting efficacy, speed and convenience of RelabotulinumtoxinA, which not only represents the innovation of our neuromodulator portfolio, but also demonstrates our commitment to responding to the real needs of healthcare professionals and patients.”

 

BALDO SCASSELLATI SFORZOLINI, M.D., Ph.D.

GLOBAL HEAD OF R&D

GALDERMA

 

 

43QM2106 is a phase IIIb, randomized, double-blind, placebo-controlled trial to assess the aesthetic improvement and onset of action of RelabotulinumtoxinA in patients with moderate to severe frown lines. The trial met its primary endpoint, with 92.9% of those treated with RelabotulinumtoxinA rating their frown lines as ‘improved’ or better on the Global Aesthetic Improvement Scale (GAIS) at month one, compared to 9.1% of those treated with placebo (P<0.001).1

Results reinforced the rapid onset of action and durability of RelabotulinumtoxinA, with 40% of patients rating themselves as ‘improved’ or better on the GAIS as early as day one, and more than a third (38%) of patients rating themselves as ‘improved’ or better at month 12. In addition, 68% and 43% of patients rated themselves as ‘improved’ or better at months six and nine respectively, and 40% of patients also reported at least a one grade improvement of frown line severity at month nine. RelabotulinumtoxinA was well tolerated; the majority of patients did not experience any adverse events and there were no related serious adverse events reported.1

43QM2107 is a phase IIIb, open-label, single-center study to assess aesthetic improvement of RelabotulinumtoxinA in patients with moderate to severe crow’s feet and frown lines. It also met its primary endpoint, with 100% of patients treated with RelabotulinumtoxinA rating their crow’s feet and frown lines as ‘improved’ or better on the GAIS at month one.2

RelabotulinumtoxinA demonstrated a rapid onset of action for both crow’s feet and frown lines, with the majority of patients (68% and 60% for crow’s feet and frown lines, respectively) rating themselves as ‘improved’ or better on the GAIS starting at day one. By day two, 100% of patients noted improvement for crow’s feet and 96% noted improvement for frown lines. This was reinforced by Subject Live Assessment results using a validated scale, which showed that 40% of patients on day one and 96% of patients on day four received a score of zero or one on a four-point scale for crow’s feet severity at maximum expression. For frown line severity, 32% of patients on day one and 92% of patients on day four received a score of zero or one. RelabotulinumtoxinA was well tolerated, with no adverse events reported in 92% of patients.2

Results from both studies are in line with those previously seen for RelabotulinumtoxinA.3,4

About RelabotulinumtoxinA (QM1114) 

Developed by Galderma, RelabotulinumtoxinA is a highly-active, innovative, complex-free, and ready-to-use liquid botulinum toxin A with a proprietary strain and manufactured using a unique state-of-the-art process. It is designed as a liquid, avoiding the traditional requirement to reconstitute from powder and eliminating variability, errors and risks associated with reconstitution, which would be expected to improve the consistency of results. RelabotulinumtoxinA is currently being investigated globally by Galderma to expand its neuromodulator portfolio as part of the broadest Injectable Aesthetics portfolio on the market.

About Galderma 

Galderma is the emerging pure-play dermatology category leader, present in approximately 90 countries. We deliver an innovative, science-based portfolio of premium flagship brands and services that span the full spectrum of the fast-growing dermatology market though Injectable Aesthetics, Dermatological Skincare and Therapeutic Dermatology. Since our foundation in 1981, we have dedicated our focus and passion to the human body’s largest organ – the skin – meeting individual consumer and patient needs with superior outcomes in partnership with healthcare professionals. Because we understand that the skin we are in shapes our lives, we are advancing dermatology for every skin story. For more information: www.galderma.com.

References:

Galderma data on file: initial results of the phase IIIb 43QM2106 trial

Galderma data on file: initial results of the phase IIIb 43QM2107 trial

Shridharani, S., et al. Treatment of moderate-to-severe glabellar lines with RelabotulinumtoxinA, a new liquid botulinum toxin: Clinical efficacy and safety results from the READY-1 Phase III trial. Poster presented at Vegas Cosmetic Surgery & Aesthetic Dermatology 2022, Las Vegas, NV, June 8-11, 2022

Ibrahim, SF, et al. Treatment of lateral canthal lines with RelabotulinumtoxinA, a new liquid botulinum toxin: Clinical efficacy and safety results from the READY-2 Phase III trial. Poster presented at Vegas Cosmetic Surgery & Aesthetic Dermatology 2022, Las Vegas, NV, June 8-11, 2022.

 

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Contacts

Christian Marcoux, M.Sc.

Chief Communications Officer

christian.marcoux@galderma.com

+41 76 315 26 50

Sébastien Cros

Corporate Communications Director

sebastien.cros@galderma.com

+41 79 529 59 85

Emil Ivanov

Head of Strategy, Investor Relations, and ESG

emil.ivanov@galderma.com

+41 21 642 78 12

Jessica Cohen

Investor Relations and Strategy Director

jessica.cohen@galderma.com

+41 21 642 76 43